Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR132 | Q9UNW8 | 7/20 | 0.63 |
| ▸ | ACE | P12821 | 2/20 | 0.53 |
| ▸ | CMKLR2 | P46091 | 1/20 | 0.52 |
| ▸ | CMKLR1 | Q99788 | 1/20 | 0.52 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.50 |
| ▸ | TACR1 | P25103 | 1/20 | 0.49 |
| ▸ | LNPEP | Q9UIQ6 | 2/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.48 |
| ▸ | MME | P08473 | 1/20 | 0.48 |
| ▸ | CPA1 | P15085 | 1/20 | 0.48 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.48 |
| ▸ | HPGDS | O60760 | 1/20 | 0.48 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.48 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.48 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7553966 | 0.91 | GPR132 (0.58) | GPR132ACECMKLR2CMKLR1LNPEP | |
| SCHEMBL7511099 | 0.89 | ACE (0.64) | GPR132ACETACR1LNPEPHPGDS | |
| SCHEMBL7523142 | 0.80 | ACE (0.50) | GPR132ACETACR1LNPEPHPGDS | |
| SCHEMBL1123158 | 0.80 | GPR132 (0.77) | GPR132CMKLR2CMKLR1SMPD1LNPEP | |
| SCHEMBL14617723 | 0.79 | MME (0.56) | GPR132ACESMPD1TACR1PTPN1 | |
| SCHEMBL1123379 | 0.78 | GPR132 (0.95) | GPR132CMKLR2CMKLR1SMPD1PTPN1 | |
| SCHEMBL1123382 | 0.78 | GAA (0.71) | GPR132CMKLR2CMKLR1LNPEPPTPN1 | |
| SCHEMBL7709601 | 0.78 | LNPEP (0.50) | GPR132ACETACR1LNPEPERAP2 | |
| SCHEMBL7709356 | 0.78 | ACE (0.50) | ACELNPEPMMEHPGDSERAP2 | |
| SCHEMBL7709445 | 0.77 | ACE (0.70) | GPR132ACETACR1LNPEPPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6362165-B1 | Hydroxyphenyl derivatives with HIV integrase inhibitory properties | PHARMACOR INC. (CA) | 2002-03-26 | — | — | US | disclosed |