Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.30 |
| ▸ | BCHE | P06276 | 1/20 | 0.30 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.30 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.30 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5603824 | 0.70 | ADRA2C (0.33) | — | |
| Hydrochloric Acid SCHEMBL9016923 | 0.68 | POLB (0.34) | CYP19A1 | |
| Hydrochloric Acid SCHEMBL217506 | 0.67 | ADRA2C (0.33) | — | |
| Hydrochloric Acid SCHEMBL4062480 | 0.67 | BCHE (0.30) | BCHEACHE | |
| Hydrochloric Acid SCHEMBL15732725 | 0.66 | — | — | |
| Hydrochloric Acid SCHEMBL7645544 | 0.63 | BCHE (0.30) | BCHEACHE | |
| SCHEMBL27585047 | 0.63 | ACHE (0.33) | BCHEACHE | |
| Hydrochloric Acid SCHEMBL218728 | 0.63 | ADRA2C (0.36) | CYP19A1CYP11B1CYP11B2 | |
| Hydrochloric Acid SCHEMBL5611348 | 0.63 | MAPK1 (0.31) | BCHEACHE | |
| Hydrochloric Acid SCHEMBL7203977 | 0.62 | ESR1 (0.37) | CYP19A1CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020156209-A1 | Polymerization in the presence of metallocene catalysts with bridged bis-indenyl compounds | BASELL TECHNOLOGY COMANY BV (NL) | 2002-10-24 | — | — | US | disclosed |