Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK10 | P53779 | 1/20 | 0.43 |
| ▸ | ILK | Q13418 | 2/20 | 0.42 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.39 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.36 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.35 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4199489 | 0.85 | KMT2A (0.37) | TDP1CYP1A2CYP2D6CYP2C19ALDH1A1 | |
| SCHEMBL4192472 | 0.81 | NPC1 (0.46) | MAPK10CYP3A4CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL4187924 | 0.81 | RAB9A (0.36) | TDP1CYP1A2CYP2D6CYP2C19ALDH1A1 | |
| SCHEMBL1005758 | 0.80 | MAPK8 (0.46) | MAPK10ILKMKNK1MKNK2CYP3A4 | |
| SCHEMBL4190183 | 0.80 | MAPT (0.40) | CYP3A4CYP1A2CYP2D6CYP2C19ALDH1A1 | |
| Acetonitrile SCHEMBL7707679 | 0.80 | RAB9A (0.35) | TDP1CYP1A2CYP2D6CYP2C19ALDH1A1 | |
| SCHEMBL4192273 | 0.80 | MAPK9 (0.39) | MAPK10ILKTDP1CYP1A2CYP2D6 | |
| SCHEMBL4197422 | 0.79 | SMN1; SMN2 (0.41) | ILKMKNK1MKNK2TDP1CYP1A2 | |
| SCHEMBL4187935 | 0.79 | ILK (0.38) | ILKMKNK1MKNK2CYP1A2CYP2D6 | |
| SCHEMBL4190281 | 0.79 | ALDH1A1 (0.40) | ILKCYP3A4CYP1A2CYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1240164-A1 | BENZAZOLE DERIVATIVES AND THEIR USE AS JNK MODULATORS | Applied Research Systems ARS Holding N.V. (AN) | 2002-09-18 | — | — | EP | claimed |
| WO-2001047920-A1 | BENZAZOLE DERIVATIVES AND THEIR USE AS JNK MODULATORS | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2001-07-05 | — | — | WO | claimed |