Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | VCP | P55072 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GPR6 | P46095 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7711282 | 0.87 | OPRK1 (0.46) | ALDH1A1KDM4ENPC1RAB9AMAPT | |
| SCHEMBL7719028 | 0.84 | MYC (0.44) | ALDH1A1KDM4ENPC1RAB9AMAPT | |
| SCHEMBL7716779 | 0.80 | CHRM4 (0.47) | SMN1; SMN2VCP | |
| SCHEMBL28965451 | 0.78 | KDM4E (0.56) | ALDH1A1KDM4ENPC1RAB9AMAPT | |
| SCHEMBL23611761 | 0.77 | KDM4E (0.58) | ALDH1A1KDM4ENPC1RAB9AMAPT | |
| SCHEMBL7718924 | 0.75 | TSHR (0.51) | RAB9AHPGDDRD2DRD3 | |
| SCHEMBL7711167 | 0.73 | NPC1 (0.56) | ALDH1A1KDM4ENPC1MAPTALOX15 | |
| SCHEMBL16896437 | 0.73 | CKS1B (0.48) | KDM4EDRD2 | |
| SCHEMBL7715998 | 0.73 | NPY5R (0.46) | VCP | |
| SCHEMBL853123 | 0.71 | ALDH1A1 (0.54) | ALDH1A1KDM4ENPC1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6376503-B1 | TREATMENT OF BENIGN PROSTATIC HYPERPLASIA | MERCK & CO., INC | 2002-04-23 | — | — | US | disclosed |