Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | DRD2 | P14416 | 5/20 | 0.48 |
| ▸ | DRD3 | P35462 | 4/20 | 0.48 |
| ▸ | DRD4 | P21917 | 2/20 | 0.48 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | HTR1D | P28221 | 1/20 | 0.47 |
| ▸ | HTR1B | P28222 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7719028 | 0.84 | MYC (0.44) | TSHRHPGDRAB9A | |
| SCHEMBL7714962 | 0.82 | ADRA1A (0.47) | DRD2 | |
| SCHEMBL7714901 | 0.81 | DRD2 (0.50) | DRD2DRD3 | |
| SCHEMBL7711167 | 0.81 | NPC1 (0.56) | — | |
| SCHEMBL24124019 | 0.81 | DRD2 (0.50) | TSHRDRD2DRD3 | |
| SCHEMBL20140998 | 0.79 | MCOLN2 (0.55) | HPGDDRD2DRD3DRD4HTR1A | |
| SCHEMBL26418374 | 0.79 | DRD2 (0.51) | DRD2DRD3 | |
| SCHEMBL8125499 | 0.79 | HTR1A (0.59) | TSHRHPGDDRD2DRD3HTR1A | |
| SCHEMBL7715922 | 0.79 | DRD4 (0.47) | DRD2DRD3DRD4 | |
| SCHEMBL7716782 | 0.78 | DRD2 (0.69) | DRD2DRD3DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6376503-B1 | TREATMENT OF BENIGN PROSTATIC HYPERPLASIA | MERCK & CO., INC | 2002-04-23 | — | — | US | disclosed |