Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MYC | P01106 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.43 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.43 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.43 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | XBP1 | P17861 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7711167 | 0.87 | NPC1 (0.56) | KDM4EPDCD1CD274ALDH1A1NPC1 | |
| SCHEMBL7714769 | 0.85 | OPRK1 (0.45) | MYCKDM4EBDKRB1ALDH1A1HPGD | |
| SCHEMBL7718924 | 0.84 | TSHR (0.51) | HPGDRAB9ATSHR | |
| SCHEMBL7711280 | 0.84 | ALDH1A1 (0.44) | KDM4EALDH1A1HPGDNPC1MAPT | |
| SCHEMBL13698798 | 0.79 | ALDH1A1 (0.59) | MYCKDM4EBDKRB1ALDH1A1HPGD | |
| SCHEMBL7711060 | 0.78 | DRD2 (0.51) | KDM4EOPRK1 | |
| SCHEMBL7715922 | 0.78 | DRD4 (0.47) | KDM4EPDCD1CD274ALDH1A1MAPT | |
| SCHEMBL7715013 | 0.77 | KDM4E (0.44) | KDM4EPDCD1CD274ALDH1A1KMT2A | |
| SCHEMBL28989190 | 0.76 | NPC1 (0.48) | MYCKDM4EBDKRB1ALDH1A1HPGD | |
| SCHEMBL7718948 | 0.76 | NPY1R (0.49) | KDM4EALDH1A1NPC1MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6376503-B1 | TREATMENT OF BENIGN PROSTATIC HYPERPLASIA | MERCK & CO., INC | 2002-04-23 | — | — | US | disclosed |