Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 2/20 | 0.46 |
| ▸ | PPOX | P50336 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 4/20 | 0.44 |
| ▸ | CA2 | P00918 | 4/20 | 0.44 |
| ▸ | CA12 | O43570 | 3/20 | 0.44 |
| ▸ | CA9 | Q16790 | 3/20 | 0.44 |
| ▸ | CA7 | P43166 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9194010 | 0.81 | CA2 (0.48) | MMP2CA1CA2CA12CA9 | |
| SCHEMBL7711735 | 0.79 | PPOX (0.47) | PPOXMAPT | |
| SCHEMBL7163791 | 0.79 | PPOX (0.69) | PPOXMAPTALDH1A1 | |
| SCHEMBL9807518 | 0.76 | PPOX (0.47) | PPOXLMNAMAPTALDH1A1 | |
| SCHEMBL9737247 | 0.74 | ALDH1A1 (0.62) | PPOXKDM4ELMNAMAPTHTT | |
| SCHEMBL7162462 | 0.74 | PPOX (0.45) | PPOXLMNAMAPTALDH1A1 | |
| SCHEMBL8560334 | 0.72 | TDP1 (0.50) | PPOXCA1CA12CA9KDM4E | |
| SCHEMBL10598966 | 0.72 | PPOX (0.44) | PPOXMAPT | |
| SCHEMBL9737192 | 0.72 | PPOX (0.44) | PPOX | |
| SCHEMBL11064552 | 0.72 | KAT2B (0.51) | PPOXMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-5194386-A | — | — | None | — | — | JP | disclosed |
| JP-H05194386-A | NEW COMPOUND AND HERBICIDE CONTAINING THE SAME | TAKEDA CHEM IND LTD | 1993-08-03 | — | — | JP | disclosed |