Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 1/20 | 0.43 |
| ▸ | CCR3 | P51677 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | XBP1 | P17861 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | NPY2R | P49146 | 2/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.39 |
| ▸ | FABP3 | P05413 | 1/20 | 0.38 |
| ▸ | FABP4 | P15090 | 1/20 | 0.38 |
| ▸ | ME3 | Q16798 | 1/20 | 0.38 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7715013 | 0.85 | KDM4E (0.44) | HRH1CCR3KCNH2KDM4EKMT2A | |
| SCHEMBL7711170 | 0.80 | NPC1 (0.55) | KDM4EKMT2AMEN1CYP1A2CYP2D6 | |
| SCHEMBL7714769 | 0.77 | OPRK1 (0.45) | KDM4EKMT2ACHRM2CHRM5CHRM3 | |
| SCHEMBL7715920 | 0.76 | ADRB1 (0.45) | KDM4EKMT2AMEN1CHRM2CHRM5 | |
| SCHEMBL2553609 | 0.75 | CKS1B (0.54) | HRH1CCR3KCNH2KMT2A | |
| SCHEMBL8683997 | 0.75 | FABP3 (0.55) | HRH1CCR3KCNH2KDM4EKMT2A | |
| SCHEMBL7714987 | 0.74 | KDM4E (0.44) | KDM4E | |
| SCHEMBL7718950 | 0.73 | NPY1R (0.50) | KDM4EKMT2AMEN1NPSR1 | |
| SCHEMBL7718916 | 0.73 | NPY1R (0.50) | KDM4EKMT2AMEN1NPSR1 | |
| Bromide SCHEMBL8998015 | 0.73 | FABP3 (0.53) | HRH1CCR3KCNH2KDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6376503-B1 | TREATMENT OF BENIGN PROSTATIC HYPERPLASIA | MERCK & CO., INC | 2002-04-23 | — | — | US | disclosed |