Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY1R | P25929 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 7/20 | 0.46 |
| ▸ | CTPS1 | P17812 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | GRM5 | P41594 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7718916 | 0.82 | NPY1R (0.50) | NPY1RLMNAALDH1A1MAPTL3MBTL1 | |
| SCHEMBL7718950 | 0.82 | NPY1R (0.50) | NPY1RLMNAALDH1A1MAPTL3MBTL1 | |
| SCHEMBL7711167 | 0.80 | NPC1 (0.56) | LMNAALDH1A1MAPTKMT2AHTT | |
| SCHEMBL3436153 | 0.79 | MAPT (0.68) | LMNAALDH1A1MAPTCTPS1L3MBTL1 | |
| SCHEMBL5092054 | 0.79 | MAPT (0.55) | LMNAALDH1A1MAPTCTPS1L3MBTL1 | |
| SCHEMBL7715922 | 0.78 | DRD4 (0.47) | ALDH1A1MAPTPOLBKMT2AGAA | |
| SCHEMBL7711275 | 0.77 | NPY1R (0.54) | NPY1RLMNAALDH1A1MAPTKMT2A | |
| SCHEMBL7715013 | 0.77 | KDM4E (0.44) | ALDH1A1KMT2AMEN1KDM4ECYP1A2 | |
| SCHEMBL7718924 | 0.77 | TSHR (0.51) | RAB9A | |
| SCHEMBL3436163 | 0.76 | LMNA (0.49) | LMNAALDH1A1MAPTCTPS1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6376503-B1 | TREATMENT OF BENIGN PROSTATIC HYPERPLASIA | MERCK & CO., INC | 2002-04-23 | — | — | US | disclosed |