Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 1/20 | 0.45 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.43 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7714901 | 0.82 | DRD2 (0.50) | ADRB1DRD2ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL7714987 | 0.80 | KDM4E (0.44) | DRD2ALDH1A1KDM4EDRD3C5AR1 | |
| SCHEMBL7711170 | 0.78 | NPC1 (0.55) | DRD2ALDH1A1SMN1; SMN2CHRM1KDM4E | |
| SCHEMBL7714769 | 0.78 | OPRK1 (0.45) | TSHRDRD2ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL7718916 | 0.77 | NPY1R (0.50) | ALDH1A1SMN1; SMN2KDM4EKMT2AMEN1 | |
| SCHEMBL7718950 | 0.77 | NPY1R (0.50) | ALDH1A1SMN1; SMN2KDM4EKMT2AMEN1 | |
| SCHEMBL3436641 | 0.76 | ADRB1 (0.51) | ADRB1SLC18A3TSHRALDH1A1HPGD | |
| SCHEMBL7715017 | 0.76 | HRH1 (0.43) | KDM4EKMT2AMEN1CHRM2CHRM5 | |
| SCHEMBL7716756 | 0.76 | DRD2 (0.51) | NPY5RDRD2CHRM1KDM4EUSP2 | |
| SCHEMBL7714964 | 0.74 | ADRA1A (0.44) | DRD2ALDH1A1KDM4EADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6376503-B1 | TREATMENT OF BENIGN PROSTATIC HYPERPLASIA | MERCK & CO., INC | 2002-04-23 | — | — | US | disclosed |