SCHEMBL9915635

SCHEMBL9915635

[C-]#[N+]c1cc(/C=C/c2ccc(N(c3ccccc3)c3ccccc3)cc2)c(C#N)cc1/C=C/c1ccc(N(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.38

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
APP P05067 2/20 0.38
PRKCQ Q04759 3/20 0.35
PRKCD Q05655 2/20 0.35
RELA Q04206 1/20 0.33
SLC16A3 O15427 1/20 0.31
SLC16A1 P53985 1/20 0.31
ALDH1A1 P00352 1/20 0.31
HPGD P15428 1/20 0.31
ALOX12 P18054 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
MAOA P21397 1/20 0.30
MAOB P27338 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12202183 0.88 ALDH1A1 (0.38) PRKCQPRKCDALDH1A1HPGDALOX12
SCHEMBL9915842 0.88 APP (0.46) APPPRKCQPRKCDRELASLC16A3
SCHEMBL7716038 0.88 APP (0.46) APPPRKCQPRKCDRELASLC16A3
SCHEMBL12258640 0.84 PTGS1 (0.35) APPPRKCQPRKCDSLC16A3SLC16A1
SCHEMBL12258700 0.81 TRPA1 (0.37) APPRELASLC16A3SLC16A1ALDH1A1
SCHEMBL14436330 0.81 RELA (0.56) APPPRKCQPRKCDRELAALDH1A1
SCHEMBL14436656 0.81 APP (0.44) APPPRKCQPRKCDRELASLC16A3
SCHEMBL14436331 0.81 NFE2L2 (0.43) APPPRKCQPRKCDRELAALDH1A1
SCHEMBL14436657 0.81 APP (0.44) APPPRKCQPRKCDRELASLC16A3
SCHEMBL812329 0.80 NFE2L2 (0.39) RELAALDH1A1HPGDALOX12L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8197722-B2 Irradiating the compound (containing two electron donor groups and a bridge of pi-conjugated bonds containing electron donor groups) with light, and the compound is converted to a multi-photon electronically excited state THE CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2012-06-12 US disclosed
US-7790353-B2 Multidirectional photoreactive absorption method 3M INNOVATIVE PROPERTIES COMPANY (US) 2010-09-07 US disclosed
US-7790347-B2 Multi-photon reacted articles with inorganic particles and method for fabricating structures 3M INNOVATIVE PROPERTIES COMPANY (US) 2010-09-07 US disclosed
US-20100207078-A1 DEPROTECTION OF FUNCTIONAL GROUPS BY MULTI-PHOTON INDUCED ELECTRON TRANSFER THE ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA 2010-08-19 US disclosed
US-7733012-B2 Light-emitting device and aromatic compound FUJIFILM CORPORATION (JP) 2010-06-08 US disclosed
US-7655376-B2 Multibeam interference; pyrolysis; chemical vapor deposition 3M INNOVATIVE PROPERTIES COMPANY (US) 2010-02-02 US disclosed
US-7582685-B2 a curable mixture of polysilazanes, sulfur compounds, vinyl silanes, vinyl esters or (meth)acrylates, and photosensitizers, used to provide heat reistant ceramic-based microstructures, such as combustion chambers, heat exchangers, detectors and actuators, microfluidics and optics 3M INNOVATIVE PROPERTIES COMPANY (US) 2009-09-01 US disclosed
US-7517592-B2 Light-emitting device and aromatic compound FUJIFILM CORPORATION (JP) 2009-04-14 US disclosed
US-20090035528-A1 Multi-photon reacted articles with inorganic particles and method for fabricating structures 3M INNOVATIVE PROPERTIES COMPANY 2009-02-05 US disclosed
US-20080233430-A1 LIGHT-EMITTING DEVICE AND AROMATIC COMPOUND FUJIFILM CORPORATION (JP) 2008-09-25 US disclosed
US-20080152948-A1 LIGHT-EMITTING DEVICE AND AROMATIC COMPOUND FUJIFILM CORPORATION (JP) 2008-06-26 US disclosed
US-7332477-B2 Photocleavable DNA transfer agent NITTO DENKO CORPORATION (JP) 2008-02-19 US disclosed
US-20070282030-A1 Multibeam interference; pyrolysis; chemical vapor deposition 3M INNOVATIVE PROPERTIES COMPANY 2007-12-06 US disclosed
US-7297374-B1 Single- and multi-photon polymerizable pre-ceramic polymeric compositions 3M INNOVATIVE PROPERTIES COMPANY (US) 2007-11-20 US disclosed
US-20070264501-A1 MULTI-PHOTON REACTIVE COMPOSITIONS WITH INORGANIC PARTICLES AND METHOD FOR FABRICATING STRUCTURES 3M INNOVATIVE PROPERTIES COMPANY 2007-11-15 US disclosed
US-20070254975-A1 SINGLE- AND MULTI-PHOTON POLYMERIZABLE PRE-CERAMIC POLYMERIC COMPOSITIONS 3M INNOVATIVE PROPERTIES COMPANY 2007-11-01 US disclosed
US-7265161-B2 Multi-photon reactive compositions with inorganic particles and method for fabricating structures 3M INNOVATIVE PROPERTIES COMPANY (US) 2007-09-04 US disclosed
US-7261952-B2 Red color emitting compounds for organic electroluminescent device and an organic electroluminescent device using them LG ELECTRONICS INC. (KR) 2007-08-28 US disclosed
US-20070087284-A1 MULTIPASS MULTIPHOTON ABSORPTION METHOD AND APPARATUS 3M INNOVATIVE PROPERTIES COMPANY 2007-04-19 US disclosed
US-7166409-B2 Multipass multiphoton absorption method and apparatus 3M INNOVATIVE PROPERTIES COMPANY (US) 2007-01-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100207078-A1 DEPROTECTION OF FUNCTIONAL GROUPS BY MULTI-PHOTON INDUCED ELECTRON TRANSFER GPX4, ERCC4, CYBA APP 2910/4885PRKCQ 2700/4885PRKCD 3620/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.