Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 3/20 | 0.32 |
| ▸ | PTGES | O14684 | 1/20 | 0.32 |
| ▸ | MMP13 | P45452 | 1/20 | 0.31 |
| ▸ | STAT3 | P40763 | 1/20 | 0.30 |
| ▸ | STAT5B | P51692 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3850225 | 0.97 | P2RX7 (0.32) | P2RX7PTGESMMP13STAT3STAT5B | |
| SCHEMBL3851526 | 0.93 | PTGES (0.36) | P2RX7PTGES | |
| SCHEMBL3855576 | 0.91 | MMP13 (0.32) | P2RX7MMP13 | |
| SCHEMBL3855318 | 0.91 | P2RX7 (0.32) | P2RX7MMP13 | |
| SCHEMBL3849839 | 0.89 | P2RX7 (0.30) | P2RX7 | |
| SCHEMBL3849629 | 0.89 | P2RX7 (0.33) | P2RX7 | |
| SCHEMBL5609494 | 0.89 | — | — | |
| SCHEMBL3855348 | 0.88 | MMP2 (0.33) | P2RX7PTGES | |
| SCHEMBL3851221 | 0.86 | TAS2R14 (0.34) | — | |
| SCHEMBL3860129 | 0.86 | ADAMTS5 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6489300-B1 | INHIBITORS OF ADHESION IN THE TREATMENT OF INFLAMMATORY BRAIN DISEASES AND OTHER INFLAMMATORY CONDITIONS | ELAN PHARMACEUTICALS, INC. | 2002-12-03 | — | — | US | disclosed |