SCHEMBL772025

SCHEMBL772025

CS(=O)(=O)N1CCCCC1

nearest known ligand 0.55

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.55
CA2 P00918 2/20 0.55
POLB P06746 1/20 0.55
TSHR P16473 3/20 0.52
KMT2A Q03164 3/20 0.52
USP2 O75604 1/20 0.44
KDM4E B2RXH2 1/20 0.44
LMNA P02545 2/20 0.42
MEN1 O00255 2/20 0.42
CYP3A4 P08684 1/20 0.41
CYP2C9 P11712 1/20 0.41
CYP2C19 P33261 1/20 0.41
GAA P10253 1/20 0.40
TP53 P04637 1/20 0.40
ALDH1A1 P00352 2/20 0.39
HTT P42858 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14907235 1.00 CA1 (0.55) CA1CA2POLBTSHRKMT2A
SCHEMBL1521784 1.00 CA1 (0.55) CA1CA2POLBTSHRKMT2A
SCHEMBL2101944 1.00 CA1 (0.55) CA1CA2POLBTSHRKMT2A
SCHEMBL13565616 1.00 CA1 (0.55) CA1CA2POLBTSHRKMT2A
Hydrochloric Acid SCHEMBL16830708 0.97 CA1 (0.52) CA1CA2POLBTSHRKMT2A
Ammonia Solution, Strong SCHEMBL4301662 0.97 CA1 (0.52) CA1CA2POLBTSHRKMT2A
SCHEMBL12988565 0.97
SCHEMBL171574 0.97
SCHEMBL3123076 0.90
SCHEMBL12989189 0.90

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1155 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025024564-A1 SMALL MOLECULES THAT PREVENT STATIN-INDUCED ACCUMULATION OF HMG COA REDUCTASE THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) 2025-01-30 WO claimed
EP-4100408-B1 TRICYCLIC HETEROARYL COMPOUNDS USEFUL AS IRAK4 INHIBITORS BRISTOL MYERS SQUIBB CO (US) 2024-02-28 EP claimed
US-20240018154-A1 NEW INDAZOLE DERIVATIVES HOFFMANN-LA ROCHE INC. (US) 2024-01-18 US claimed
CN-114126713-B Substituted benzimidazolone compounds 百时美施贵宝公司 2023-12-08 CN claimed
WO-2023209441-A1 IMIDAZO[4,5-C]PYRIDINE DERIVATIVE COMPOUNDS AS TLR7/8 MODULATORS LEGOCHEM BIOSCIENCES, INC. (KR) 2023-11-02 WO claimed
US-11787785-B2 Pyrazolopyridine derivatives and uses thereof NOVARTIS AG (CH) 2023-10-17 US claimed
EP-4255906-A1 NEW INDAZOLE DERIVATIVES F. Hoffmann-La Roche AG (CH) 2023-10-11 EP claimed
US-20230212131-A1 COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF ANIMA BIOTECH INC. (US) 2023-07-06 US claimed
EP-4161921-A1 COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF Anima Biotech Inc. (US) 2023-04-12 EP claimed
US-20230108325-A1 Pyrazolopyridine Derivatives and Uses thereof NOVARTIS AG (CH) 2023-04-06 US claimed
CN-100413861-C Compounds and methods for the treatment or prevention of flavivirus infections VIROCHEM PHARMA INC (CA) 2008-08-27 CN claimed
US-20080119497-A1 Hydroxyalkyl substituted pyrido-7-pyrimidin-7-ones ROCHE PALO ALTO LLC 2008-05-22 US claimed
US-7348331-B2 Hydroxyalkyl substituted pyrido-7-pyrimidin-7-ones ROCHE PALO ALTO LLC (US) 2008-03-25 US claimed
EP-1343771-B1 3-OX(ADI)AZOLYLPROPANOHYDROXAMIC ACIDS USEFUL AS PROCOLLAGEN C-PROTEINASE INHIBITORS PFIZER LTD (GB) 2006-04-12 EP claimed
US-20050107408-A1 Hydroxyalkyl substituted pyrido-7-pyrimidin-7-ones ROCHE PALO ALTO LLC 2005-05-19 US claimed
US-20040142986-A1 3-ox(adi)azolylpropanohydroxamic acids useful as procollagen C-proteinase inhibitors DATTA USA (GB) 2004-07-22 US claimed
EP-1343771-A1 3-OX(ADI)AZOLYLPROPANOHYDROXAMIC ACIDS USEFUL AS PROCOLLAGEN C-PROTEINASE INHIBITORS Pfizer Limited (GB) 2003-09-17 EP claimed
US-20020151535-A1 3-ox(adi) azolylpropanohydroxamic acids useful as procollagen C- Proteinase inhibitors PFIZER, INC 2002-10-17 US claimed
WO-2002050046-A1 3-OX(ADI)AZOLYLPROPANOHYDROXAMIC ACIDS USEFUL AS PROCOLLAGEN C-PROTEINASE INHIBITORS PFIZER LIMITED (GB) 2002-06-27 WO claimed
CN-1035179-C New indol derivatives ALMIRALL LAB (ES) 1997-06-18 CN claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240018154-A1 NEW INDAZOLE DERIVATIVES CYP3A43, CYP3A4, CYP3A5 CA1 3092/4885CA2 1293/4885POLB 4605/4885
US-20080119497-A1 Hydroxyalkyl substituted pyrido-7-pyrimidin-7-ones MAPK1, MAPK7, MAPK6 CA1 4866/4885CA2 4720/4885POLB 1085/4885
US-11787785-B2 Pyrazolopyridine derivatives and uses thereof HBZ, ZFX, WIZ CA1 4813/4885CA2 3395/4885POLB 981/4885
US-20230212131-A1 COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF COL1A1, COL2A1, COL14A1 CA1 4669/4885CA2 4469/4885POLB 554/4885
US-20020151535-A1 3-ox(adi) azolylpropanohydroxamic acids useful as procollagen C- Proteinase inhibitors ALPI, TIMP3, MMP1 CA1 127/4885CA2 184/4885POLB 3127/4885
US-20050107408-A1 Hydroxyalkyl substituted pyrido-7-pyrimidin-7-ones MAPK1, MAPK7, MAPK6 CA1 4866/4885CA2 4720/4885POLB 1085/4885
US-20230108325-A1 Pyrazolopyridine Derivatives and Uses thereof HBZ, ZFX, WIZ CA1 4813/4885CA2 3395/4885POLB 981/4885
US-20040142986-A1 3-ox(adi)azolylpropanohydroxamic acids useful as procollagen C-proteinase inhibitors ALPI, TIMP3, MMP1 CA1 127/4885CA2 184/4885POLB 3127/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.