Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S100A4 | P26447 | 5/20 | 0.56 |
| ▸ | CDC25B | P30305 | 4/20 | 0.56 |
| ▸ | NSD2 | O96028 | 4/20 | 0.44 |
| ▸ | TDP2 | O95551 | 1/20 | 0.44 |
| ▸ | ABL1 | P00519 | 1/20 | 0.44 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 1/20 | 0.44 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.44 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | PTPRC | P08575 | 2/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | CTSS | P25774 | 1/20 | 0.41 |
| ▸ | PTPN13 | Q12923 | 1/20 | 0.41 |
| ▸ | PADI1 | Q9ULC6 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7721594 | 0.74 | PADI1 (0.50) | S100A4CDC25BNSD2TDP2ABL1 | |
| SCHEMBL7719640 | 0.74 | S100A4 (0.50) | S100A4CDC25BNSD2TDP2ABL1 | |
| SCHEMBL31362908 | 0.74 | S100A4 (1.00) | S100A4CDC25BNSD2TDP2ABL1 | |
| SCHEMBL1612462 | 0.74 | S100A4 (1.00) | S100A4CDC25BNSD2TDP2ABL1 | |
| SCHEMBL16745449 | 0.73 | S100A4 (0.77) | S100A4CDC25BNSD2TDP2ABL1 | |
| SCHEMBL5915065 | 0.72 | TDP2 (0.81) | S100A4CDC25BNSD2TDP2ABL1 | |
| SCHEMBL7690116 | 0.69 | S100A4 (0.69) | S100A4CDC25BNSD2TDP2ABL1 | |
| SCHEMBL6294370 | 0.68 | S100A4 (0.87) | S100A4CDC25BNSD2TDP2ABL1 | |
| SCHEMBL9267635 | 0.68 | TDP2 (0.74) | S100A4CDC25BNSD2TDP2ABL1 | |
| SCHEMBL16745450 | 0.68 | S100A4 (0.61) | S100A4CDC25BNSD2TDP2ABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6391064-B1 | DYEING HAIR WITH AMINE QUINOLONE DERIVATIVES | L'OREAL S.A. (FR) | 2002-05-21 | — | — | US | claimed |
| EP-0984010-B1 | Use in hair dyes of quinolin-5,8-diones or quinoxalin-5,8-diones condensed with substituted pyrroles, anilines or indoles | OREAL (FR) | 2001-06-20 | — | — | EP | claimed |
| EP-0984010-A1 | Use in hair dyes of quinolin-5,8-diones or quinoxalin-5,8-diones condensed with substituted pyrroles, anilines or indoles | L'OREAL (FR) | 2000-03-08 | — | — | EP | claimed |
| US-6391064-B1 | DYEING HAIR WITH AMINE QUINOLONE DERIVATIVES | L'OREAL S.A. (FR) | 2002-05-21 | — | — | US | disclosed |
| EP-0984010-B1 | Use in hair dyes of quinolin-5,8-diones or quinoxalin-5,8-diones condensed with substituted pyrroles, anilines or indoles | OREAL (FR) | 2001-06-20 | — | — | EP | disclosed |
| EP-0984010-A1 | Use in hair dyes of quinolin-5,8-diones or quinoxalin-5,8-diones condensed with substituted pyrroles, anilines or indoles | L'OREAL (FR) | 2000-03-08 | — | — | EP | disclosed |