SCHEMBL7720531

SCHEMBL7720531

c1ccc(COc2ccnc(OCc3ccccc3)c2OCc2ccccc2)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 1/20 0.49
MAPK14 Q16539 1/20 0.49
ABCB1 P08183 1/20 0.47
L3MBTL1 Q9Y468 2/20 0.46
MAPK1 P28482 2/20 0.46
MAPT P10636 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
HTR1A P08908 1/20 0.43
DRD2 P14416 1/20 0.43
LIPE Q05469 1/20 0.42
LMNA P02545 2/20 0.41
HTT P42858 2/20 0.41
ALDH1A1 P00352 1/20 0.41
HPGD P15428 1/20 0.41
TSHR P16473 1/20 0.41
PDE5A O76074 1/20 0.41
GAA P10253 1/20 0.41
STAT3 P40763 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
PLAU P00749 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8529216 0.87 MEN1 (0.46) LTA4HMAPK14ABCB1L3MBTL1MAPK1
SCHEMBL4898749 0.81 L3MBTL1 (0.53) LTA4HMAPK14ABCB1L3MBTL1MAPK1
SCHEMBL29013146 0.81 SMN1; SMN2 (0.54) LTA4HMAPK14ABCB1L3MBTL1MAPK1
SCHEMBL7713506 0.79 L3MBTL1 (0.46) LTA4HMAPK14ABCB1L3MBTL1MAPK1
SCHEMBL24215198 0.78 L3MBTL1 (0.53) LTA4HMAPK14ABCB1L3MBTL1MAPK1
SCHEMBL9654512 0.78 LTA4H (0.45) LTA4HMAPK14ABCB1L3MBTL1MAPK1
SCHEMBL4898090 0.78 LTA4H (0.45) LTA4HMAPK14ABCB1L3MBTL1MAPK1
SCHEMBL8526782 0.78 LTA4H (0.66) LTA4HMAPK14ABCB1L3MBTL1MAPK1
SCHEMBL4890014 0.77 KDM4E (0.47) LTA4HMAPK14ALDH1A1HPGDSGMS2
Hydrochloric Acid SCHEMBL9683438 0.77 LTA4H (0.44) LTA4HMAPK14ABCB1L3MBTL1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11787959-B2 Radiation curable gravure ink CHANGZHOU GREEN PHOTOSENSITIVE MATERIALS CO., LTD. (CN) 2023-10-17 US disclosed
US-20230133556-A1 BENZOXAZINES AND COMPOSITIONS CONTAINING THE SAME CYTEC INDUSTRIES INC 2023-05-04 US disclosed
US-11566106-B2 Composite materials containing benzoxazines and method for making the same CYTEC INDUSTRIES INC. (US) 2023-01-31 US disclosed
US-20210115276-A1 Radiation curable Gravure Ink CHANGZHOU GREEN PHOTOSENSITIVE MAT CO LTD (CN) 2021-04-22 US disclosed
EP-3770221-A1 RADIATION-CURABLE GRAVURE INK Changzhou Green Photosensitive Materials Co., Ltd. (CN) 2021-01-27 EP disclosed
US-20200291179-A1 COMPOSITE MATERIALS CONTAINING BENZOXAZINES AND METHOD FOR MAKING THE SAME CYTEC INDUSTRIES INC. (US) 2020-09-17 US disclosed
EP-3240829-B1 BENZOXAZINES AND COMPOSITIONS CONTAINING THE SAME CYTEC IND INC (US) 2019-08-21 EP disclosed
EP-3240829-A1 BENZOXAZINES AND COMPOSITIONS CONTAINING THE SAME Cytec Industries Inc. (US) 2017-11-08 EP disclosed
US-9732225-B2 Benzoxazine resins CYTEC TECHNOLOGY CORP. (US) 2017-08-15 US disclosed
WO-2016109399-A1 BENZOXAZINES AND COMPOSITIONS CONTAINING THE SAME CYTEC INDUSTRIES INC. (US) 2016-07-07 WO disclosed
US-20160185908-A1 BENZOXAZINES AND COMPOSITIONS CONTAINING THE SAME CYTEC INDUSTRIES INC. (US) 2016-06-30 US disclosed
US-20160115317-A1 BENZOXAZINE RESINS CYTEC TECHNOLOGY CORP. (US) 2016-04-28 US disclosed
US-9255075-B2 Benzoxazine resins CYTEC TECHNOLOGY CORP. (US) 2016-02-09 US disclosed
EP-2668238-B1 BENZOXAZINE RESINS CYTEC TECH CORP (US) 2014-11-19 EP disclosed
US-20130345352-A1 Benzoxazine Resins CYTEC TECHNOLOGY CORP. (US) 2013-12-26 US disclosed
EP-2668238-A1 BENZOXAZINE RESINS Cytec Technology Corp. (US) 2013-12-04 EP disclosed
WO-2012100980-A1 BENZOXAZINE RESINS CYTEC TECHNOLOGY CORP. (US) 2012-08-02 WO disclosed
US-6376080-B1 HEATING A BENZOXAZINE; ACID CATALYST LOCTITE CORPORATION 2002-04-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200291179-A1 COMPOSITE MATERIALS CONTAINING BENZOXAZINES AND METHOD FOR MAKING THE SAME F12, COL1A1, BRIX1 LTA4H 888/4885MAPK14 2209/4885ABCB1 803/4885
US-11566106-B2 Composite materials containing benzoxazines and method for making the same F12, COL1A1, BRIX1 LTA4H 888/4885MAPK14 2209/4885ABCB1 803/4885
US-20230133556-A1 BENZOXAZINES AND COMPOSITIONS CONTAINING THE SAME F12, BRIX1, COL1A1 LTA4H 1497/4885MAPK14 2185/4885ABCB1 421/4885
US-20130345352-A1 Benzoxazine Resins BAZ1A, SMARCA1, SMARCA5 LTA4H 678/4885MAPK14 2417/4885ABCB1 238/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.