Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AAK1 | Q2M2I8 | 5/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.37 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.36 |
| ▸ | MAP1LC3A | Q9H492 | 1/20 | 0.36 |
| ▸ | CTSS | P25774 | 4/20 | 0.35 |
| ▸ | CTSK | P43235 | 4/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | CTSB | P07858 | 2/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7721375 | 0.89 | KDM4E (0.43) | AAK1HDAC4HDAC1MAPTSMN1; SMN2 | |
| Methane SCHEMBL7718636 | 0.86 | HDAC4 (0.46) | AAK1HDAC4HDAC1MAPTSMN1; SMN2 | |
| SCHEMBL7714829 | 0.82 | AAK1 (0.38) | AAK1HDAC1HDAC8HDAC3HDAC2 | |
| SCHEMBL7718633 | 0.75 | ALDH1A1 (0.47) | HDAC4HDAC1MAPTSMN1; SMN2HDAC8 | |
| SCHEMBL7719355 | 0.72 | HDAC4 (0.46) | AAK1HDAC4HDAC1MAPTSMN1; SMN2 | |
| SCHEMBL7719351 | 0.72 | HDAC4 (0.46) | AAK1HDAC4HDAC1MAPTSMN1; SMN2 | |
| SCHEMBL487103 | 0.69 | MEN1 (0.43) | AAK1MAPTALDH1A1TSHR | |
| SCHEMBL29663697 | 0.68 | ITGB3 (0.52) | HDAC8CTSSCTSKCTSB | |
| SCHEMBL7714050 | 0.68 | CA12 (0.41) | HDAC1MAPTHDAC8KDM4EALDH1A1 | |
| SCHEMBL22193729 | 0.67 | CTSS (0.53) | HDAC8CTSSCTSKCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6441017-B1 | Inhibitors of prenyl-protein transferase | MERCK & CO., INC. | 2002-08-27 | — | — | US | disclosed |