Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
| ▸ | KMO | O15229 | 1/20 | 0.34 |
| ▸ | PPIA | P62937 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 2/20 | 0.33 |
| ▸ | CNR2 | P34972 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2530090 | 0.95 | HDAC4 (0.39) | HDAC4HDAC2HDAC8CHRNB2CHRNA4 | |
| SCHEMBL6004412 | 0.84 | HDAC4 (0.50) | HDAC4HDAC2HDAC8CHRNB2CHRNA4 | |
| SCHEMBL7531576 | 0.84 | HDAC4 (0.50) | HDAC4HDAC2HDAC8CHRNB2CHRNA4 | |
| SCHEMBL5275279 | 0.83 | HDAC4 (0.38) | HDAC4HDAC2HDAC8CHRNB2CHRNA4 | |
| SCHEMBL3169205 | 0.82 | HDAC4 (0.52) | HDAC4HDAC2HDAC8CHRNB2CHRNA4 | |
| SCHEMBL7721762 | 0.82 | HDAC4 (0.37) | HDAC4HDAC2HDAC8CHRNB2CHRNA4 | |
| SCHEMBL28717708 | 0.78 | GABRA1 (0.36) | HDAC4HDAC2HDAC8ALDH1A1ALOX15 | |
| SCHEMBL29558450 | 0.78 | GABRA1 (0.36) | HDAC4HDAC2HDAC8ALDH1A1ALOX15 | |
| SCHEMBL4961704 | 0.77 | CHRNB2 (0.53) | HDAC4HDAC2HDAC8CHRNB2CHRNA4 | |
| SCHEMBL4958023 | 0.77 | CHRNB2 (0.53) | HDAC4HDAC2HDAC8CHRNB2CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5434031-A | Positive-working naphthoquinone diazide photoresist composition containing specific hydroxy compound additive | TOKYO OHKA KOGYO CO., LTD. (JP) | 1995-07-18 | — | — | US | disclosed |