Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | IAPP | P10997 | 1/20 | 0.42 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.40 |
| ▸ | CES1 | P23141 | 1/20 | 0.40 |
| ▸ | BID | P55957 | 3/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.39 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.39 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.39 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | EP300 | Q09472 | 1/20 | 0.39 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.39 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14402655 | 0.87 | RIPK1 (0.46) | KMT2AMEN1ALDH1A1IAPPRIPK1 | |
| SCHEMBL1538027 | 0.81 | VNN1 (0.48) | KMT2AMEN1ALDH1A1HTTIAPP | |
| SCHEMBL8388641 | 0.80 | RIPK1 (0.48) | KMT2AMEN1IAPPRIPK1CES2 | |
| SCHEMBL6666485 | 0.80 | CES2 (0.48) | KMT2AMEN1ALDH1A1RIPK1CES2 | |
| SCHEMBL4451515 | 0.76 | P2RX7 (0.50) | KMT2AMAPTMEN1CES2CES1 | |
| SCHEMBL4463081 | 0.76 | P2RX7 (0.50) | KMT2AMAPTMEN1CES2CES1 | |
| SCHEMBL8746425 | 0.75 | LIPG (0.50) | KMT2AMAPTMEN1HTTBID | |
| SCHEMBL7533430 | 0.75 | LIPG (0.50) | KMT2AMAPTMEN1HTTBID | |
| SCHEMBL4819280 | 0.75 | LIPG (0.50) | KMT2AMAPTMEN1HTTBID | |
| SCHEMBL4286994 | 0.75 | LIPG (0.50) | KMT2AMAPTMEN1HTTBID |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6391397-B1 | ELECTRO-OPTICAL LIQUID CRYSTAL DEVICE; FLUORINATED PHENYL COMPOUNDS;4?-DECYLOXY-2,3-DIFLUORO-4-(2,2-DIFLUOROOCTYL)-1,1': 4',1?-TERPHENYL | SHARP KABUSHIKI KAISHA (JP) | 2002-05-21 | — | — | US | disclosed |
| EP-1044952-A2 | High transverse dipole moment aryl compounds | SHARP KABUSHIKI KAISHA (JP) | 2000-10-18 | — | — | EP | disclosed |