Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 9/20 | 0.59 |
| ▸ | BCHE | P06276 | 4/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7734278 | 0.88 | DRD2 (0.46) | ACHEBCHEKMT2ASIGMAR1 | |
| SCHEMBL7732470 | 0.84 | SIGMAR1 (0.48) | ACHEBCHESIGMAR1 | |
| SCHEMBL7736003 | 0.81 | MEN1 (0.48) | KMT2ASIGMAR1 | |
| SCHEMBL4327969 | 0.79 | TEAD1 (0.58) | SIGMAR1 | |
| SCHEMBL13814798 | 0.78 | BCHE (0.67) | ACHEBCHEKMT2ASIGMAR1KDM4E | |
| SCHEMBL4157854 | 0.77 | ACHE (0.68) | ACHEBCHEKMT2ASIGMAR1KDM4E | |
| SCHEMBL7732370 | 0.75 | KDM4E (0.67) | ACHEBCHEKMT2AKDM4E | |
| SCHEMBL28946798 | 0.75 | KMT2A (0.69) | ACHEBCHEKMT2AKDM4E | |
| SCHEMBL7493236 | 0.75 | KMT2A (0.69) | ACHEBCHEKMT2AKDM4E | |
| SCHEMBL8528754 | 0.75 | SLC18A3 (0.46) | SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6399619-B1 | PREVENTION AND TREATMENT OF AIDS AND VIRAL INFECTION BY HIV | MERCK & CO., INC. | 2002-06-04 | — | — | US | disclosed |