Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.48 |
| ▸ | BCHE | P06276 | 2/20 | 0.42 |
| ▸ | ACHE | P22303 | 2/20 | 0.42 |
| ▸ | HTR1A | P08908 | 6/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7734278 | 0.85 | DRD2 (0.46) | SIGMAR1BCHEACHEHTR1ADRD2 | |
| SCHEMBL7723274 | 0.84 | ACHE (0.59) | SIGMAR1BCHEACHE | |
| SCHEMBL17064427 | 0.81 | SIGMAR1 (0.56) | SIGMAR1BCHEACHEHTR1ASLC6A4 | |
| SCHEMBL7736003 | 0.79 | MEN1 (0.48) | SIGMAR1HTR1ADRD2HTR2ADRD3 | |
| SCHEMBL7723348 | 0.78 | GPR119 (0.60) | SIGMAR1 | |
| Trifluoroacetic Acid SCHEMBL7732466 | 0.77 | KMT2A (0.45) | SIGMAR1BCHEACHEHTR1ASLC6A4 | |
| SCHEMBL6475939 | 0.73 | HSD11B1 (0.35) | — | |
| SCHEMBL14790689 | 0.73 | USP30 (0.39) | CHRM4 | |
| SCHEMBL6475659 | 0.71 | HSD11B1 (0.34) | — | |
| SCHEMBL7731608 | 0.71 | HDAC2 (0.40) | HTR1ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6399619-B1 | PREVENTION AND TREATMENT OF AIDS AND VIRAL INFECTION BY HIV | MERCK & CO., INC. | 2002-06-04 | — | — | US | disclosed |