Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | FLT1 | P17948 | 1/20 | 0.37 |
| ▸ | FLT4 | P35916 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | TTR | P02766 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.34 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7720719 | 0.90 | ELANE (0.40) | MAPTPOLBPKMKMT2AHSD11B1 | |
| SCHEMBL7717485 | 0.89 | KMT2A (0.43) | LMNAALDH1A1KMT2AHSD11B1FLT1 | |
| SCHEMBL7695457 | 0.86 | HSD11B1 (0.38) | MAPTLMNAALDH1A1KMT2AHSD11B1 | |
| SCHEMBL7722385 | 0.85 | LMNA (0.51) | MAPTPOLBPKMLMNAALDH1A1 | |
| SCHEMBL7693046 | 0.84 | MMP2 (0.39) | MAPTLMNAALDH1A1KMT2AHSD11B1 | |
| SCHEMBL6738564 | 0.81 | PLK1 (0.48) | TP53 | |
| SCHEMBL7696130 | 0.80 | ALPL (0.37) | MAPTLMNAKMT2AHSD11B1FLT1 | |
| SCHEMBL7724566 | 0.78 | MAPT (0.57) | MAPTPOLBPKMLMNAALDH1A1 | |
| SCHEMBL7721788 | 0.78 | MAPT (0.44) | MAPTPOLBPKMLMNAALDH1A1 | |
| SCHEMBL7720733 | 0.77 | ELANE (0.51) | MAPTPOLBPKMLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6395446-B1 | CONTAINING SULFONYLDIAZOMETHANE COMPOUND AS ACID GENERATOR | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2002-05-28 | — | — | US | disclosed |