Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | FLT1 | P17948 | 1/20 | 0.35 |
| ▸ | FLT4 | P35916 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.32 |
| ▸ | GPR27 | Q9NS67 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7724576 | 0.90 | MAPT (0.43) | ELANEKMT2AHSD11B1FLT1FLT4 | |
| SCHEMBL7724582 | 0.86 | ELANE (0.47) | ELANEKMT2ATDP1MAPTPOLB | |
| SCHEMBL7717485 | 0.86 | KMT2A (0.43) | ELANEKMT2AHSD11B1FLT1FLT4 | |
| SCHEMBL7695457 | 0.83 | HSD11B1 (0.38) | KMT2AHSD11B1FLT1FLT4KDR | |
| SCHEMBL7693046 | 0.81 | MMP2 (0.39) | KMT2AHSD11B1FLT1FLT4KDR | |
| SCHEMBL7721774 | 0.79 | ELANE (0.38) | ELANEKMT2AFFAR4TDP1MAPT | |
| SCHEMBL7717492 | 0.79 | ELANE (0.46) | ELANEKMT2ATDP1MAPTPOLB | |
| SCHEMBL7724550 | 0.78 | ELANE (0.53) | ELANEKMT2ATDP1NFE2L2MAPT | |
| SCHEMBL6738564 | 0.78 | PLK1 (0.48) | CA2 | |
| SCHEMBL7724552 | 0.78 | ELANE (0.45) | ELANEKMT2AL3MBTL1TDP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6395446-B1 | CONTAINING SULFONYLDIAZOMETHANE COMPOUND AS ACID GENERATOR | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2002-05-28 | — | — | US | disclosed |