Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | PGK1 | P00558 | 1/20 | 0.34 |
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.31 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.31 |
| ▸ | PTGFR | P43088 | 1/20 | 0.31 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.31 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.31 |
| ▸ | PTGIR | P43119 | 1/20 | 0.31 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7733881 | 0.90 | NLRP3 (0.36) | MAPTHTTPGK1LMNAAKR1B1 | |
| SCHEMBL7737540 | 0.85 | MAPT (0.44) | SMN1; SMN2MAPTPGK1LMNAALDH1A1 | |
| SCHEMBL7737446 | 0.84 | PGK1 (0.35) | PGK1AKR1B1ALDH1A1MEN1KMT2A | |
| SCHEMBL7734791 | 0.82 | RAB9A (0.39) | RAB9AAKR1B1ALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL7735654 | 0.82 | NPC1 (0.42) | MAPTLMNARAB9AMEN1KMT2A | |
| SCHEMBL7737473 | 0.81 | MEN1 (0.39) | SMN1; SMN2MAPTHTTLMNARAB9A | |
| SCHEMBL7735204 | 0.81 | PGK1 (0.38) | MAPTHTTPGK1LMNAAKR1B1 | |
| SCHEMBL7734319 | 0.80 | AKR1B1 (0.34) | MAPTPGK1RAB9AAKR1B1ALDH1A1 | |
| SCHEMBL7724872 | 0.79 | GAA (0.36) | SMN1; SMN2MAPTHTTPGK1RAB9A | |
| SCHEMBL7734848 | 0.77 | MAPT (0.38) | SMN1; SMN2MAPTHTTMBOAT4AKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6372770-B1 | TREATING A MAMMAL SUFFERING FROM A DISEASE STATE SELECTED FROM THE GROUP CONSISTING OF ASTHMA, ALLERGIES, INFLAMMATION, DEPRESSION, DEMENTIA, ATOPIC DISEASES, RHINITIS AND DISEASE STATES ASSOCIATED WITH ABNORMALLY HIGH PHYSIOLOGICAL LEVELS OF | EURO-CELTIQUE, S.A. | 2002-04-16 | — | — | US | claimed |