Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 7/20 | 0.42 |
| ▸ | RAB9A | P51151 | 6/20 | 0.42 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7737473 | 0.91 | MEN1 (0.39) | NPC1RAB9AKMT2ALMNATP53 | |
| SCHEMBL7737540 | 0.87 | MAPT (0.44) | NPC1KMT2ALMNATP53MAPT | |
| SCHEMBL7737446 | 0.86 | PGK1 (0.35) | KMT2AMEN1 | |
| SCHEMBL7733881 | 0.83 | NLRP3 (0.36) | LMNAMAPTPTK2 | |
| SCHEMBL7734760 | 0.82 | MAPT (0.42) | NPC1RAB9AKMT2ALMNAMAPT | |
| SCHEMBL7724886 | 0.82 | SMN1; SMN2 (0.35) | RAB9AKMT2ALMNATP53MAPT | |
| SCHEMBL7724872 | 0.81 | GAA (0.36) | NPC1RAB9AKMT2AMAPTMEN1 | |
| SCHEMBL7734791 | 0.80 | RAB9A (0.39) | NPC1RAB9APKMKMT2A | |
| SCHEMBL7679979 | 0.79 | DHFR (0.34) | NPC1RAB9AKMT2ALMNATP53 | |
| SCHEMBL7735271 | 0.79 | MAOB (0.41) | NPC1RAB9ALMNATP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6372770-B1 | TREATING A MAMMAL SUFFERING FROM A DISEASE STATE SELECTED FROM THE GROUP CONSISTING OF ASTHMA, ALLERGIES, INFLAMMATION, DEPRESSION, DEMENTIA, ATOPIC DISEASES, RHINITIS AND DISEASE STATES ASSOCIATED WITH ABNORMALLY HIGH PHYSIOLOGICAL LEVELS OF | EURO-CELTIQUE, S.A. | 2002-04-16 | — | — | US | disclosed |
| EP-0785927-A4 | NOVEL BENZOXAZOLES | EURO CELTIQUE SA (LU) | 1997-12-29 | — | — | EP | disclosed |
| EP-0785927-A1 | NOVEL BENZOXAZOLES | Euroceltique S.A. (LU) | 1997-07-30 | — | — | EP | disclosed |
| WO-1996011917-A1 | NOVEL BENZOXAZOLES | EURO-CELTIQUE, S.A. (LU) | 1996-04-25 | — | — | WO | disclosed |