Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | STAT3 | P40763 | 1/20 | 0.34 |
| ▸ | PGK1 | P00558 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.32 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7737473 | 0.92 | MEN1 (0.39) | MAPTPOLBKMT2ALMNATSHR | |
| SCHEMBL7735654 | 0.87 | NPC1 (0.42) | MAPTKMT2ALMNAMEN1TP53 | |
| SCHEMBL7734760 | 0.85 | MAPT (0.42) | MAPTPOLBKMT2ALMNATSHR | |
| SCHEMBL7724886 | 0.85 | SMN1; SMN2 (0.35) | MAPTKMT2ALMNAUSP2L3MBTL1 | |
| SCHEMBL7737446 | 0.84 | PGK1 (0.35) | KMT2AMEN1ALDH1A1PGK1 | |
| SCHEMBL7733881 | 0.83 | NLRP3 (0.36) | MAPTLMNATSHRL3MBTL1KDM4E | |
| SCHEMBL7679979 | 0.82 | DHFR (0.34) | MAPTKMT2ALMNATSHRMEN1 | |
| SCHEMBL7734791 | 0.81 | RAB9A (0.39) | POLBKMT2AL3MBTL1ALDH1A1NPC1 | |
| SCHEMBL7724872 | 0.80 | GAA (0.36) | MAPTPOLBKMT2AL3MBTL1MEN1 | |
| SCHEMBL7734319 | 0.78 | AKR1B1 (0.34) | MAPTKMT2ATSHRL3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6372770-B1 | TREATING A MAMMAL SUFFERING FROM A DISEASE STATE SELECTED FROM THE GROUP CONSISTING OF ASTHMA, ALLERGIES, INFLAMMATION, DEPRESSION, DEMENTIA, ATOPIC DISEASES, RHINITIS AND DISEASE STATES ASSOCIATED WITH ABNORMALLY HIGH PHYSIOLOGICAL LEVELS OF | EURO-CELTIQUE, S.A. | 2002-04-16 | — | — | US | claimed |