Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 5/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | HTT | P42858 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | UBE2N | P61088 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7724719 | 0.91 | JAK2 (0.45) | JAK2LMNAMAPTALDH1A1HTT | |
| SCHEMBL7730172 | 0.88 | LMNA (0.51) | JAK2LMNAMAPTALDH1A1KDM4E | |
| SCHEMBL7726296 | 0.88 | JAK2 (0.45) | JAK2LMNAMAPTALDH1A1HTT | |
| SCHEMBL7720344 | 0.88 | PLA2G2A (0.51) | LMNAMAPTALDH1A1KDM4ENPC1 | |
| SCHEMBL7720154 | 0.87 | JAK2 (0.44) | JAK2LMNAMAPTALDH1A1HTT | |
| SCHEMBL7723640 | 0.87 | ALDH1A1 (0.52) | JAK2LMNAMAPTALDH1A1HTT | |
| SCHEMBL7720252 | 0.86 | ALDH1A1 (0.47) | JAK2LMNAMAPTALDH1A1HTT | |
| SCHEMBL7723582 | 0.85 | ALDH1A1 (0.44) | JAK2LMNAMAPTALDH1A1HTT | |
| SCHEMBL7720270 | 0.85 | MAPT (0.59) | LMNAMAPTALDH1A1HTTNPC1 | |
| SCHEMBL7723523 | 0.85 | CRHR1 (0.51) | JAK2LMNAALDH1A1HTTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6403586-B1 | Pyridazine derivatives and drugs containing the same as the active ingredient | KOWA CO., LTD. (JP) | 2002-06-11 | — | — | US | disclosed |
| EP-1061077-A1 | NOVEL PYRIDAZINE DERIVATIVES AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | Kowa Co., Ltd. (JP) | 2000-12-20 | — | — | EP | disclosed |
| US-6090568-A | Format for minimizing interferences in chemiluminescent thin-film immunoassays | CLINICAL DIAGNOSTIC SYSTEMS, INC. (US) | 2000-07-18 | — | — | US | disclosed |
| US-5714340-A | LAYER CONTAINING LABELED LIGAND, BEAD SPREADING LAYER, CROSSLINKED HYDROPHILIC POLYMER LAYER AND A SUPPORT | JOHNSON & JOHNSON CLINICAL DIAGNOSTICS, INC. (US) | 1998-02-03 | — | — | US | disclosed |
| US-5696193-A | WATER SOLUBLE POLYMER; SPREADING LAYER ON IMMUNOASSAYANALYTICAL ELEMENT | CLINICAL DIAGNOSTIC SYSTEMS, INC. (US) | 1997-12-09 | — | — | US | disclosed |
| US-5516645-A | Immunoassay analytical elements containing vanadium IV(V+4)ions | JOHNSON & JOHNSON CLINICAL DIAGNOSTICS, INC. (US) | 1996-05-14 | — | — | US | disclosed |
| US-5482831-A | Wash composition containing signal stop reagent, test kit and method of use with peroxidase-labeled specific binding ligand | JOHNSON & JOHNSON CLINICAL DIAGNOSTICS, INC. (US) | 1996-01-09 | — | — | US | disclosed |
| US-5399484-A | Immunoassay | EASTMAN KODAK COMPANY (US) | 1995-03-21 | — | — | US | disclosed |
| US-5391483-A | Using mixture of periodic acid and chromium trioxide | EASTMAN KODAK COMPANY (US) | 1995-02-21 | — | — | US | disclosed |
| US-5387510-A | Probes; complementarity; hybridization | EASTMAN KODAK COMPANY (US) | 1995-02-07 | — | — | US | disclosed |
| US-5155021-A | METHOD AND KIT FOR DETERMINATION OF HERPES SIMPLEX VIRAL ANTIGEN BY DIRECT BINDING TO POLYMERIC PARTICLES | EASTMAN KODAK COMPANY (US) | 1992-10-13 | — | — | US | disclosed |
| US-5132085-A | Medical test device designed so that a representative word or symbol is formed | EASTMAN KODAK COMPANY (US) | 1992-07-21 | — | — | US | disclosed |
| US-5094962-A | Streptococcus | EASTMAN KODAK COMPANY (US) | 1992-03-10 | — | — | US | disclosed |
| EP-0468591-A2 | Ligand analogs for immunoassays derived from dicarboxylic acid oxidation products | Johnson & Johnson Clinical Diagnostics, Inc. (US) | 1992-01-29 | — | — | EP | disclosed |
| EP-0467466-A1 | Method for the purification of immunoreactive labeled thyroxine conjugates | EASTMAN KODAK COMPANY (US) | 1992-01-22 | — | — | EP | disclosed |
| US-5077198-A | DIAGNOSTIC KIT AND METHOD FOR RAPID DETECTION OF ANTIBODIES | EASTMAN KODAK COMPANY (US) | 1991-12-31 | — | — | US | disclosed |
| US-5053443-A | Methods of preparing a polymeric latex composition and water-insoluble biological reagent | EASTMAN KODAK COMPANY (US) | 1991-10-01 | — | — | US | disclosed |
| US-4997772-A | Shell-core polymers | EASTMAN KODAK COMPANY (US) | 1991-03-05 | — | — | US | disclosed |
| WO-1989009939-A1 | COMPOSITIONS, DIAGNOSTIC KIT AND METHOD FOR RAPID DETECTION OF ANTIBODIES | EASTMAN KODAK COMPANY (US) | 1989-10-19 | — | — | WO | disclosed |
| EP-0308233-A2 | Method of preparing a polymeric latex composition | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1989-03-22 | — | — | EP | disclosed |