Sugi Predict

Sugi Predict / Compounds / SCHEMBL772537

SCHEMBL772537

SCHEMBL772537

CCC1(C(=O)O)CCCN(C(=O)OC(C)(C)C)C1

nearest known ligand 0.43

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ USP2 O75604 1/20 0.43
▸ SMN1; SMN2 Q16637 1/20 0.43
▸ MMP2 P08253 1/20 0.42
▸ MMP13 P45452 1/20 0.42
▸ MMP14 P50281 1/20 0.42
▸ ADAM17 P78536 1/20 0.42
▸ HPGD P15428 1/20 0.40
▸ MEN1 O00255 3/20 0.39
▸ KMT2A Q03164 3/20 0.39
▸ ALDH1A1 P00352 1/20 0.38
▸ MAPT P10636 1/20 0.38
▸ CYP4F2 P78329 1/20 0.37
▸ CYP4A11 Q02928 1/20 0.37
▸ CTSK P43235 1/20 0.36
▸ USP30 Q70CQ3 2/20 0.36
▸ RECQL P46063 1/20 0.36
▸ EPHX1 P07099 1/20 0.36
▸ SCD5 Q86SK9 1/20 0.35
▸ NR1H2 P55055 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL772536 1.00 USP2 (0.43) USP2SMN1; SMN2MMP2MMP13MMP14
SCHEMBL17075655 1.00 USP2 (0.43) USP2SMN1; SMN2MMP2MMP13MMP14
SCHEMBL34474243 0.91 USP2 (0.45) USP2SMN1; SMN2CYP4F2CYP4A11USP30
SCHEMBL22978724 0.89 MMP2 (0.42) USP2SMN1; SMN2MMP2MMP13MMP14
SCHEMBL17075656 0.89 CYP4F2 (0.45) USP2SMN1; SMN2MMP2MMP13MMP14
SCHEMBL25272101 0.87 MMP2 (0.41) USP2SMN1; SMN2MMP2MMP13MMP14
SCHEMBL17371376 0.86 MMP2 (0.43) USP2SMN1; SMN2MMP2MMP13MMP14
SCHEMBL3497339 0.86 MMP2 (0.41) USP2SMN1; SMN2MMP2MMP13MMP14
SCHEMBL2888789 0.85 L3MBTL1 (0.47) USP2SMN1; SMN2MMP2MMP13MMP14
SCHEMBL4581228 0.85 USP2 (0.46) USP2SMN1; SMN2HPGDMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250289808-A1 NOVEL CARBOXAMIDE REDOX DERIVATIVE OF INHIBITING BET PROTEIN AND COMPOSITION FOR PREVENTING AND TREATING OPHTHALMIC DISEASES USING THE SAME BenoBio Co., Ltd (KR) 2025-09-18 — — US disclosed
EP-4613329-A1 COMPOUND FOR INHIBITING BRD PROTEIN Benobio Co., Ltd. (KR) 2025-09-10 — — EP disclosed
CN-109996792-B Heterocyclic compounds having activity as modulators of muscarinic M1 and/or M4 receptors in the treatment of CNS diseases and pain 赫普泰雅治疗有限公司 2023-02-17 — — CN disclosed
CN-109937204-B Spiro-lactam NMDA receptor modulators and uses thereof 阿普廷伊克斯股份有限公司 2022-11-25 — — CN disclosed
CN-113329791-A 9-substituted amino-triazoloquinazoline derivatives as adenosine receptor antagonists, pharmaceutical compositions and uses thereof 默沙东公司 2021-08-31 — — CN disclosed
US-11091436-B2 Process for the separation of optical isomers of racemic 3-alkylpiperidine-carboxylic acid ethyl esters RICHTER GEDEON NYRT. (HU) 2021-08-17 — — US disclosed
US-20200131126-A1 Process for the Separation of Optical Isomers of Racemic 3-Alkylpiperidine-Carboxylic Acid Ethyl Esters RICHTER GEDEON NYRT. (HU) 2020-04-30 — — US disclosed
US-9403831-B2 Triazolopyrazine derivative and use thereof KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 2016-08-02 — — US disclosed
US-20150259350-A1 NOVEL TRIAZOLOPYRAZINE DERIVATIVE AND USE THEREOF HANDOK INC. (KR) 2015-09-17 — — US disclosed
EP-2261210-B1 3-SUBSTITUTED SULFONYL PIPERAZINE DERIVATIVE MSD KK (JP) 2014-10-22 — — EP disclosed
US-8367698-B2 3-substituted sulfonyl piperidine derivative MSD K.K. (JP) 2013-02-05 — — US disclosed
US-20120232109-A1 3-SUBSTITUTED SULFONYL PIPERIDINE DERIVATIVE NAGASE TSUYOSHI (JP) 2012-09-13 — — US disclosed
US-8188280-B2 3-substituted sulfonyl piperidine derivative MSD K.K. (JP) 2012-05-29 — — US disclosed
US-20120070409-A1 TETRACYCLIC FUSED HETEROCYCLIC COMPOUND AND USE THEREOF AS HCV POLYMERASE INHIBITOR JAPAN TOBACCO INC. (JP) 2012-03-22 — — US disclosed
US-7977331-B1 Tetracyclic fused heterocyclic compound and use thereof as HCV polymerase inhibitor JAPAN TOBACCO INC. (JP) 2011-07-12 — — US disclosed
US-20100331360-A1 3-SUBSTITUTED SULFONYL PIPERIDINE DERIVATIVE MSD K.K. (JP) 2010-12-30 — — US disclosed
EP-2261210-A1 3-SUBSTITUTED SULFONYL PIPERAZINE DERIVATIVE Banyu Pharmaceutical Co., Ltd. (JP) 2010-12-15 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150259350-A1 NOVEL TRIAZOLOPYRAZINE DERIVATIVE AND USE THEREOF MET, RET, BRAF USP2 3594/4885SMN1; SMN2 3983/4885MMP2 1690/4885
US-20120070409-A1 TETRACYCLIC FUSED HETEROCYCLIC COMPOUND AND USE THEREOF AS HCV POLYMERASE INHIBITOR POLI, TERT, ZC3HAV1 USP2 3512/4885SMN1; SMN2 4306/4885MMP2 543/4885
US-20100331360-A1 3-SUBSTITUTED SULFONYL PIPERIDINE DERIVATIVE H1-3, H1-0, H1-2 USP2 3504/4885SMN1; SMN2 353/4885MMP2 3135/4885
US-11091436-B2 Process for the separation of optical isomers of racemic 3-alkylpiperidine-carboxylic acid ethyl esters ARHGDIA, ALDH1A2, AKR1C3 USP2 3531/4885SMN1; SMN2 3559/4885MMP2 1773/4885
US-20250289808-A1 NOVEL CARBOXAMIDE REDOX DERIVATIVE OF INHIBITING BET PROTEIN AND COMPOSITION FOR PREVENTING AND TREATING OPHTHALMIC DISEASES USING THE SAME BET1, BRD4, BRD3 USP2 2653/4885SMN1; SMN2 4362/4885MMP2 2689/4885
US-20120232109-A1 3-SUBSTITUTED SULFONYL PIPERIDINE DERIVATIVE H1-3, H1-0, H1-2 USP2 3504/4885SMN1; SMN2 353/4885MMP2 3135/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.