Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | FAAH | O00519 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | CTSL | P07711 | 1/20 | 0.42 |
| ▸ | CTSB | P07858 | 1/20 | 0.42 |
| ▸ | PTGIR | P43119 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7724779 | 0.84 | MAPT (0.53) | L3MBTL1LMNACRHR1MAPTPOLB | |
| SCHEMBL7724785 | 0.83 | LMNA (0.45) | L3MBTL1LMNACRHR1MAPTALDH1A1 | |
| SCHEMBL7730352 | 0.82 | MAPT (0.67) | L3MBTL1LMNAMAPTPOLBALDH1A1 | |
| SCHEMBL7730097 | 0.82 | LMNA (0.48) | L3MBTL1LMNAMAPTPOLBALDH1A1 | |
| SCHEMBL7726527 | 0.81 | CRHR1 (0.45) | L3MBTL1LMNACRHR1ALDH1A1RAB9A | |
| SCHEMBL7723511 | 0.80 | MAPT (0.51) | L3MBTL1LMNACRHR1MAPTPOLB | |
| SCHEMBL7730095 | 0.79 | MAPT (0.55) | L3MBTL1LMNAMAPTPOLBKDM4E | |
| SCHEMBL7724970 | 0.79 | CRHR1 (0.49) | L3MBTL1LMNACRHR1MAPTPOLB | |
| SCHEMBL7723691 | 0.79 | CRHR1 (0.49) | L3MBTL1LMNACRHR1MAPTPOLB | |
| SCHEMBL7723523 | 0.78 | CRHR1 (0.51) | L3MBTL1LMNACRHR1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6403586-B1 | Pyridazine derivatives and drugs containing the same as the active ingredient | KOWA CO., LTD. (JP) | 2002-06-11 | — | — | US | disclosed |
| EP-1061077-A1 | NOVEL PYRIDAZINE DERIVATIVES AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | Kowa Co., Ltd. (JP) | 2000-12-20 | — | — | EP | disclosed |