Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 11/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7732119 | 0.82 | SLC2A1 (0.44) | — | |
| SCHEMBL7732103 | 0.78 | RAB9A (0.53) | NPC1RAB9A | |
| Trifluoroacetic Acid SCHEMBL7735917 | 0.74 | RAB9A (0.48) | NPC1RAB9A | |
| SCHEMBL7732373 | 0.73 | TRPV1 (0.50) | NPC1RAB9A | |
| SCHEMBL7732335 | 0.72 | CES1 (0.49) | — | |
| SCHEMBL7732052 | 0.72 | RAB9A (0.43) | NPC1RAB9A | |
| SCHEMBL7733996 | 0.70 | NPC1 (0.50) | NPC1RAB9A | |
| SCHEMBL7735550 | 0.69 | TRPV1 (0.52) | NPC1RAB9A | |
| SCHEMBL7732173 | 0.68 | TRPM8 (0.36) | NPC1RAB9A | |
| SCHEMBL7734013 | 0.67 | NPC1 (0.45) | NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6436980-B1 | TRANSPORT PROTEIN SUPPRESSORS; MICROBIOCIDES | ESSENTIAL THERAPEUTICS, INC. | 2002-08-20 | — | — | US | disclosed |
| US-6204279-B1 | SECONDARY AMIDE CONTAINING BENZOXAZOLE DERIVATIVES | MICROCIDE PHARMACEUTICALS, INC. | 2001-03-20 | — | — | US | disclosed |
| WO-1999037667-A1 | EFFLUX PUMP INHIBITORS | MICROCIDE PHARMACEUTICALS, INC. (US) | 1999-07-29 | — | — | WO | disclosed |