Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 6/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | CFTR | P13569 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.35 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.35 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.33 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.33 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7736280 | 0.89 | DAGLA (0.34) | CYSLTR2CYSLTR1SMN1; SMN2SLC7A5DAGLA | |
| SCHEMBL7732103 | 0.77 | RAB9A (0.53) | HDAC4HDAC1HDAC3HDAC7HDAC2 | |
| Trifluoroacetic Acid SCHEMBL7735917 | 0.75 | RAB9A (0.48) | SCN9AHDAC4TRPV1NPC1MAPT | |
| SCHEMBL7732373 | 0.71 | TRPV1 (0.50) | TRPV1NPC1MAPTNFKB1RAB9A | |
| SCHEMBL7732335 | 0.71 | CES1 (0.49) | HDAC1HDAC8HDAC6DAGLA | |
| SCHEMBL7723241 | 0.70 | HDAC4 (0.40) | SCN9AHDAC4HDAC1HDAC3HDAC7 | |
| SCHEMBL7733996 | 0.69 | NPC1 (0.50) | TRPV1NPC1MAPTNFKB1RAB9A | |
| SCHEMBL7730488 | 0.68 | BCHE (0.40) | NPC1RAB9A | |
| SCHEMBL7735550 | 0.68 | TRPV1 (0.52) | TRPV1NPC1MAPTNFKB1RAB9A | |
| SCHEMBL7732052 | 0.67 | RAB9A (0.43) | HDAC1HDAC8HDAC6NPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6436980-B1 | TRANSPORT PROTEIN SUPPRESSORS; MICROBIOCIDES | ESSENTIAL THERAPEUTICS, INC. | 2002-08-20 | — | — | US | disclosed |
| US-6204279-B1 | SECONDARY AMIDE CONTAINING BENZOXAZOLE DERIVATIVES | MICROCIDE PHARMACEUTICALS, INC. | 2001-03-20 | — | — | US | disclosed |