Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | DRD3 | P35462 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.45 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.45 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.45 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7736593 | 0.84 | HTR1A (0.46) | DRD2MAPTKMT2ALMNAALDH1A1 | |
| SCHEMBL6474943 | 0.84 | HTR1A (0.59) | DRD2LMNAHTR1AADRA1DADRA1A | |
| SCHEMBL7732082 | 0.80 | MAPT (0.46) | DRD2MAPTKMT2AMEN1LMNA | |
| SCHEMBL8129784 | 0.78 | DRD2 (0.59) | DRD2DRD3HTR1AADRA1DADRA1A | |
| SCHEMBL7736577 | 0.77 | HTR1A (0.54) | DRD2MAPTKMT2AMEN1LMNA | |
| SCHEMBL7607942 | 0.73 | HTR1A (0.58) | DRD2MAPTKMT2AMEN1LMNA | |
| SCHEMBL6936848 | 0.72 | HTR1A (0.67) | DRD2MAPTKMT2AMEN1LMNA | |
| SCHEMBL7607694 | 0.71 | DRD2 (0.67) | DRD2MAPTKMT2ALMNADRD3 | |
| SCHEMBL16690122 | 0.70 | KAT2B (0.56) | MAPTKMT2AMEN1LMNAALDH1A1 | |
| SCHEMBL7803674 | 0.70 | ADRA1A (0.69) | DRD2MAPTLMNADRD3HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6399614-B1 | TREATING NEUROMUSCULAR DYSFUNCTION OF LOWER URINARY TRACT VIA PERIPHERAL OR CENTRAL NERVOUS SYSTEM; SEROTONIN RECEPTOR ANTAGONIST | RECORDATI S.A. CHEMICAL AND PHARMACEUTICAL COMPANY (CH) | 2002-06-04 | — | — | US | disclosed |