Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.50 |
| ▸ | GFER | P55789 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 6/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | NSD2 | O96028 | 1/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | PARP14 | Q460N5 | 2/20 | 0.43 |
| ▸ | TOP1 | P11387 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8016584 | 0.86 | RXFP1 (0.50) | RXFP1KDM4EAPOBEC3AGFERHDAC1 | |
| SCHEMBL554438 | 0.84 | ALDH1A1 (0.55) | RXFP1KDM4EAPOBEC3AGFERHDAC1 | |
| SCHEMBL590479 | 0.78 | RXFP1 (0.66) | RXFP1KDM4EAPOBEC3AGFERHDAC1 | |
| SCHEMBL6746219 | 0.76 | ALDH1A1 (0.59) | RXFP1KDM4EHDAC1POLBMAPT | |
| SCHEMBL9658677 | 0.76 | KDM4E (0.51) | RXFP1KDM4EAPOBEC3AGFERHDAC1 | |
| SCHEMBL8026725 | 0.75 | KMT2A (0.49) | RXFP1KDM4EPOLBMAPTNPC1 | |
| SCHEMBL1900214 | 0.74 | RXFP1 (0.66) | RXFP1KDM4EPOLBMAPTPKM | |
| SCHEMBL1122552 | 0.74 | TRPV1 (0.58) | RXFP1KDM4EMAPTKMT2AMEN1 | |
| SCHEMBL5179041 | 0.74 | POLB (0.65) | KDM4EAPOBEC3AGFERHDAC1APOBEC3G | |
| SCHEMBL9464673 | 0.74 | CDC25B (0.55) | RXFP1KDM4EAPOBEC3AGFERHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6399787-B1 | TRANSITION METAL COMPLEX | PENN STATE RESEARCH FOUNDATION | 2002-06-04 | — | — | US | disclosed |