SCHEMBL554438

SCHEMBL554438

CC(=O)Nc1cc(C)c(O)c2ccccc12

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.55
HPGD P15428 1/20 0.55
HTT P42858 2/20 0.52
LMNA P02545 1/20 0.52
RXFP1 Q9HBX9 1/20 0.51
PKM P14618 2/20 0.49
MAPT P10636 5/20 0.48
KMT2A Q03164 4/20 0.46
MEN1 O00255 2/20 0.46
KDM4E B2RXH2 3/20 0.45
APOBEC3A P31941 1/20 0.45
GFER P55789 1/20 0.45
HDAC1 Q13547 1/20 0.45
APOBEC3G Q9HC16 1/20 0.45
MAPK1 P28482 1/20 0.44
NPC1 O15118 3/20 0.43
POLB P06746 3/20 0.43
RAB9A P51151 2/20 0.43
PARP14 Q460N5 2/20 0.42
NSD2 O96028 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7733433 0.84 RXFP1 (0.53) ALDH1A1HPGDLMNARXFP1PKM
SCHEMBL8016584 0.81 RXFP1 (0.50) ALDH1A1HPGDLMNARXFP1PKM
SCHEMBL13483433 0.77 RXFP1 (0.66) ALDH1A1HPGDRXFP1PKMMAPT
SCHEMBL14775787 0.75 TP53 (0.53) HTTKMT2AMEN1NPC1RAB9A
SCHEMBL6746219 0.75 ALDH1A1 (0.59) ALDH1A1HPGDLMNARXFP1PKM
SCHEMBL9658677 0.75 KDM4E (0.51) ALDH1A1HPGDHTTRXFP1PKM
SCHEMBL18870842 0.73 ALDH1A1 (0.41) ALDH1A1HPGDHTTLMNARXFP1
SCHEMBL14577117 0.73 ALDH1A1 (0.44) ALDH1A1HPGDMAPTKMT2AMEN1
SCHEMBL1900214 0.73 RXFP1 (0.66) ALDH1A1HPGDRXFP1PKMMAPT
Vitamin K3H2 SCHEMBL515420 0.73 HTT (0.81) ALDH1A1HPGDHTTLMNAPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0046270-B1 NOVEL DERIVATIVES OF BIO-AFFECTING PHENOLIC COMPOUNDS AND PHARMACEUTICAL COMPOSITION CONTAINING THEM INTERx RESEARCH CORPORATION (US) 1986-05-21 EP claimed
EP-0046270-A1 Novel derivatives of bio-affecting phenolic compounds and pharmaceutical composition containing them INTERx RESEARCH CORPORATION (US) 1982-02-24 EP claimed
US-10689330-B2 Amino acid derivatives and absorbable polymers therefrom BEZWADA BIOMEDICAL, LLC (US) 2020-06-23 US disclosed
US-20200165192-A1 AMINO ACID DERIVATIVES AND ABSORBABLE POLYMERS THEREFROM BEZWADA BIOMEDICAL LLC (US) 2020-05-28 US disclosed
US-10550072-B2 Amino acid derivatives and absorbable polymers therefrom BEZWADA BIOMEDICAL, LLC (US) 2020-02-04 US disclosed
US-20180194717-A1 AMINO ACID DERIVATIVES AND ABSORBABLE POLYMERS THEREFROM BEZWADA BIOMEDICAL LLC (US) 2018-07-12 US disclosed
EP-2673259-B1 AMINO ACID DERIVATIVES AND ABSORBABLE POLYMERS THEREFROM BEZWADA BIOMEDICAL LLC (US) 2018-04-11 EP disclosed
US-9868696-B2 Amino acid derivatives and absorbable polymers therefrom Bezwada Biomedial, LLC (US) 2018-01-16 US disclosed
US-20160257643-A1 AMINO ACID DERIVATIVES AND ABSORBABLE POLYMERS THEREFROM BEZWADA BIOMEDICAL LLC (US) 2016-09-08 US disclosed
US-9328192-B2 Bio-based monomers and polymers BEZWADA BIOMEDICAL, LLC (US) 2016-05-03 US disclosed
US-20150259464-A1 BIO-BASED MONOMERS AND POLYMERS BEZWADA BIOMEDICAL, LLC 2015-09-17 US disclosed
US-20090076174-A1 CONTROL RELEASE OF BIOLOGICALLY ACTIVE COMPOUNDS FROM MULTI-ARMED OLIGOMERS BEZWADA BIOMEDICAL, LLC (US) 2009-03-19 US disclosed
US-20090060979-A1 CONTROLLED RELEASE OF BIOLOGICALLY ACTIVE COMPOUNDS BEZWADA BIOMEDICAL, LLC 2009-03-05 US disclosed
EP-1951260-A2 FUNCTIONALIZED PHENOLIC COMPOUNDS AND ABSORBABLE THEREFROM Bezwada Biomedical LLC (US) 2008-08-06 EP disclosed
EP-1931334-A2 FUNCTIONALIZED DRUGS AND POLYMERS DERIVED THEREFROM Bezwada Biomedical LLC (US) 2008-06-18 EP disclosed
WO-2007053794-A2 FUNCTIONALIZED PHENOLIC COMPOUNDS AND ABSORBABLE THEREFROM BEZWADA BIOMEDICAL LLC (US) 2007-05-10 WO disclosed
WO-2007030538-A2 FUNCTIONALIZED DRUGS AND POLYMERS DERIVED THEREFROM BEZWADA BIOMEDICAL LLC (US) 2007-03-15 WO disclosed
US-20060172983-A1 Functionalized drugs and polymers derived therefrom BEZWADA BIOMEDICAL, LLC (US) 2006-08-03 US disclosed
US-20060173065-A1 Functionalized phenolic esters and amides and polymers therefrom BEZWADA BIOMEDICAL LLC 2006-08-03 US disclosed
EP-0046270-A1 Novel derivatives of bio-affecting phenolic compounds and pharmaceutical composition containing them INTERx RESEARCH CORPORATION (US) 1982-02-24 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150259464-A1 BIO-BASED MONOMERS AND POLYMERS FHIT, MGAM, BPGM ALDH1A1 1034/4885HPGD 133/4885HTT 3481/4885
US-20160257643-A1 AMINO ACID DERIVATIVES AND ABSORBABLE POLYMERS THEREFROM SRRM2, SLC7A1, BCAT2 ALDH1A1 3569/4885HPGD 3463/4885HTT 4360/4885
US-20090076174-A1 CONTROL RELEASE OF BIOLOGICALLY ACTIVE COMPOUNDS FROM MULTI-ARMED OLIGOMERS MME, CTSA, ALG1 ALDH1A1 1662/4885HPGD 3455/4885HTT 529/4885
US-10550072-B2 Amino acid derivatives and absorbable polymers therefrom SRRM2, SLC7A1, BCAT2 ALDH1A1 3569/4885HPGD 3463/4885HTT 4360/4885
US-10689330-B2 Amino acid derivatives and absorbable polymers therefrom SRRM2, SLC7A1, BCAT2 ALDH1A1 3569/4885HPGD 3463/4885HTT 4360/4885
US-20090060979-A1 CONTROLLED RELEASE OF BIOLOGICALLY ACTIVE COMPOUNDS GUSB, BMP2, APEH ALDH1A1 1816/4885HPGD 393/4885HTT 4661/4885
US-20060172983-A1 Functionalized drugs and polymers derived therefrom OGFR, LOX, OPRM1 ALDH1A1 972/4885HPGD 480/4885HTT 2117/4885
US-20180194717-A1 AMINO ACID DERIVATIVES AND ABSORBABLE POLYMERS THEREFROM SRRM2, SLC7A1, BCAT2 ALDH1A1 3569/4885HPGD 3463/4885HTT 4360/4885
US-20200165192-A1 AMINO ACID DERIVATIVES AND ABSORBABLE POLYMERS THEREFROM SRRM2, SLC7A1, BCAT2 ALDH1A1 3569/4885HPGD 3463/4885HTT 4360/4885
US-20060173065-A1 Functionalized phenolic esters and amides and polymers therefrom HAAO, HAO2, HCAR3 ALDH1A1 132/4885HPGD 681/4885HTT 2708/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.