SCHEMBL7733528

SCHEMBL7733528

CC1(C)OCC(C)(C(=O)OC(=O)C2(C)COC(C)(C)OC2)CO1

nearest known ligand 0.37

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
KCNA4 P22459 1/20 0.37
KCNA1 Q09470 1/20 0.37
KCNAB1 Q14722 1/20 0.37
FFAR3 O14843 1/20 0.32
ALDH1A1 P00352 1/20 0.32
TSHR P16473 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14211098 0.89 FFAR3 (0.36) KCNA4KCNA1KCNAB1FFAR3
SCHEMBL23868130 0.86 HSD17B10 (0.42) KCNA4KCNA1KCNAB1
SCHEMBL19734618 0.85 ALDH1A1 (0.35) KCNA4KCNA1KCNAB1ALDH1A1
SCHEMBL21264369 0.84 KCNA4 (0.31) KCNA4KCNA1KCNAB1
SCHEMBL14675284 0.84 EPHX1 (0.35) FFAR3ALDH1A1TSHR
SCHEMBL12145486 0.80
SCHEMBL21033826 0.80 TSHR (0.41) KCNA4KCNA1KCNAB1TSHR
SCHEMBL2073886 0.78 KCNA4 (0.31) KCNA4KCNA1KCNAB1
SCHEMBL1970312 0.78 KCNA4 (0.39) KCNA4KCNA1KCNAB1FFAR3
SCHEMBL20261666 0.77 ALDH1A1 (0.33) ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 76 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11217435-B2 Tuned synthetic dendrimer calibrants for mass spectrometry THE ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND (US) 2022-01-04 US disclosed
WO-2020128525-A1 NRTI THERAPIES THE UNIVERSITY OF LIVERPOOL (GB) 2020-06-25 WO disclosed
US-20200090917-A1 TUNED SYNTHETIC DENDRIMER CALIBRANTS FOR MASS SPECTROMETRY THE ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND 2020-03-19 US disclosed
CN-110741452-A Dendrimers for modulating magnetic properties of nanoparticles and hybrid nanoparticles formed therefrom 宾夕法尼亚州大学信托人 2020-01-31 CN disclosed
US-20190344342-A1 DENDRONS FOR TUNING THE MAGNETIC PROPERTIES OF NANOPARTICLES AND HYBRID NANOPARTICLES FORMED THEREFROM THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA 2019-11-14 US disclosed
US-20190344342-A1 DENDRONS FOR TUNING THE MAGNETIC PROPERTIES OF NANOPARTICLES AND HYBRID NANOPARTICLES FORMED THEREFROM THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA 2019-11-14 US disclosed
EP-3552220-A1 DENDRONS FOR TUNING THE MAGNETIC PROPERTIES OF NANOPARTICLES AND HYBRID NANOPARTICLES FORMED THEREFROM The Trustees Of The University Of Pennsylvania (US) 2019-10-16 EP disclosed
WO-2019156628-A1 METHOD FOR COATING A SUBSTRATE, A COATED SUBSTRATE, A MEDICAL DEVICE THEREOF, AND A METHOD CAPABLE OF KILLING A MICROBE AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2019-08-15 WO disclosed
US-10347476-B2 Tuned synthetic dendrimer calibrants for mass spectrometry THE ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND (US) 2019-07-09 US disclosed
US-10207919-B2 Hybrid nanoparticles containing dendrons, methods of producing such hybrid nanoparticles, and uses thereof RHODIA OPERATIONS (FR) 2019-02-19 US disclosed
WO-2009136853-A1 DENDRIMERS WITH INTERIOR AND EXTERIOR FUNCTIONALITIES COMPRISING OF AZIDE OR ALKYNE GROUPS FOR POST- FUNCTIONALIZATION BY HUISGEN CLICK CYCLOADDITION POLYMER FACTORY SWEDEN AB (SE) 2009-11-12 WO disclosed
US-20090182151-A1 Method for making amphiphilic dendrimers THE SCRIPPS RESEARCH INSTITUTE (US) 2009-07-16 US disclosed
US-7482389-B2 Nanoporous media with lamellar structures INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2009-01-27 US disclosed
US-7482389-B2 Nanoporous media with lamellar structures INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2009-01-27 US disclosed
US-20080233453-A1 PROTON CONDUCTOR HONDA MOTOR CO., LTD. (JP) 2008-09-25 US disclosed
US-20080233453-A1 PROTON CONDUCTOR HONDA MOTOR CO., LTD. (JP) 2008-09-25 US disclosed
US-20080200629-A1 Proton-conducting polymer HONDA MOTOR CO., LTD. (JP) 2008-08-21 US disclosed
US-20080200629-A1 Proton-conducting polymer HONDA MOTOR CO., LTD. (JP) 2008-08-21 US disclosed
US-20070117971-A1 Cellulose based optical film material and method for forming the same NATIONAL TAIWAN NORMAL UNIVERSITY (TW) 2007-05-24 US disclosed
US-20070117971-A1 Cellulose based optical film material and method for forming the same NATIONAL TAIWAN NORMAL UNIVERSITY (TW) 2007-05-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11217435-B2 Tuned synthetic dendrimer calibrants for mass spectrometry SRMS, SRM, DNMT1 KCNA4 955/4885KCNA1 1173/4885KCNAB1 1219/4885
US-10347476-B2 Tuned synthetic dendrimer calibrants for mass spectrometry SRMS, SRM, DNMT1 KCNA4 854/4885KCNA1 1032/4885KCNAB1 1099/4885
US-20070117971-A1 Cellulose based optical film material and method for forming the same PLCB3, PLCG2, PHOSPHO1 KCNA4 1278/4885KCNA1 2589/4885KCNAB1 3447/4885
US-10207919-B2 Hybrid nanoparticles containing dendrons, methods of producing such hybrid nanoparticles, and uses thereof DSTN, CD63, NCL KCNA4 3198/4885KCNA1 2027/4885KCNAB1 2258/4885
US-20200090917-A1 TUNED SYNTHETIC DENDRIMER CALIBRANTS FOR MASS SPECTROMETRY SRMS, SRM, DNMT1 KCNA4 955/4885KCNA1 1173/4885KCNAB1 1219/4885
US-20090182151-A1 Method for making amphiphilic dendrimers AOC3, CLTB, AOC1 KCNA4 2434/4885KCNA1 1657/4885KCNAB1 1130/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.