Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 9/20 | 0.43 |
| ▸ | NPC1 | O15118 | 7/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | RXRA | P19793 | 7/20 | 0.42 |
| ▸ | RXRB | P28702 | 7/20 | 0.42 |
| ▸ | RXRG | P48443 | 7/20 | 0.42 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7734862 | 0.86 | SLC22A12 (0.41) | RXRARXRBRXRGAKR1B1FFAR1 | |
| SCHEMBL7734231 | 0.84 | RAB9A (0.40) | RAB9ANPC1PKMPOLB | |
| SCHEMBL7734340 | 0.79 | ATM (0.41) | RXRARXRBRXRGAKR1B1NR4A2 | |
| SCHEMBL7733868 | 0.74 | RXRA (0.46) | RAB9ANPC1RXRARXRBRXRG | |
| SCHEMBL7734791 | 0.74 | RAB9A (0.39) | RAB9ANPC1PKMAKR1B1POLB | |
| SCHEMBL7734337 | 0.73 | NLRP3 (0.36) | AKR1B1 | |
| SCHEMBL7733875 | 0.71 | LMNA (0.41) | AKR1B1POLB | |
| SCHEMBL7734700 | 0.71 | NLRP3 (0.35) | AKR1B1 | |
| SCHEMBL7735189 | 0.71 | GAA (0.36) | RAB9ANPC1POLB | |
| SCHEMBL29444401 | 0.69 | MEN1 (0.59) | FFAR1FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6372770-B1 | TREATING A MAMMAL SUFFERING FROM A DISEASE STATE SELECTED FROM THE GROUP CONSISTING OF ASTHMA, ALLERGIES, INFLAMMATION, DEPRESSION, DEMENTIA, ATOPIC DISEASES, RHINITIS AND DISEASE STATES ASSOCIATED WITH ABNORMALLY HIGH PHYSIOLOGICAL LEVELS OF | EURO-CELTIQUE, S.A. | 2002-04-16 | — | — | US | disclosed |
| EP-0785927-A4 | NOVEL BENZOXAZOLES | EURO CELTIQUE SA (LU) | 1997-12-29 | — | — | EP | disclosed |
| EP-0785927-A1 | NOVEL BENZOXAZOLES | Euroceltique S.A. (LU) | 1997-07-30 | — | — | EP | disclosed |
| WO-1996011917-A1 | NOVEL BENZOXAZOLES | EURO-CELTIQUE, S.A. (LU) | 1996-04-25 | — | — | WO | disclosed |