Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | RXRA | P19793 | 9/20 | 0.38 |
| ▸ | RXRB | P28702 | 9/20 | 0.38 |
| ▸ | RXRG | P48443 | 7/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.38 |
| ▸ | NR4A2 | P43354 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7733878 | 0.86 | RAB9A (0.43) | FFAR1FFAR4RXRARXRBRXRG | |
| SCHEMBL7735189 | 0.85 | GAA (0.36) | ALDH1A1KDM4E | |
| SCHEMBL7734869 | 0.79 | ALDH1A1 (0.38) | ALDH1A1KDM4EAKR1B1 | |
| SCHEMBL7734855 | 0.77 | SIRT2 (0.34) | SLC22A12AKR1B1 | |
| SCHEMBL7724872 | 0.75 | GAA (0.36) | ALDH1A1KDM4E | |
| SCHEMBL7734340 | 0.74 | ATM (0.41) | ALDH1A1KDM4ERXRARXRBRXRG | |
| SCHEMBL7733868 | 0.74 | RXRA (0.46) | FFAR1RXRARXRBRXRGNR4A2 | |
| SCHEMBL11139559 | 0.70 | KDM4E (0.59) | FFAR1FFAR4KDM4EAKR1B1 | |
| SCHEMBL7734337 | 0.68 | NLRP3 (0.36) | AKR1B1 | |
| SCHEMBL7733875 | 0.67 | LMNA (0.41) | AKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6372770-B1 | TREATING A MAMMAL SUFFERING FROM A DISEASE STATE SELECTED FROM THE GROUP CONSISTING OF ASTHMA, ALLERGIES, INFLAMMATION, DEPRESSION, DEMENTIA, ATOPIC DISEASES, RHINITIS AND DISEASE STATES ASSOCIATED WITH ABNORMALLY HIGH PHYSIOLOGICAL LEVELS OF | EURO-CELTIQUE, S.A. | 2002-04-16 | — | — | US | claimed |