Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3A | P46098 | 3/20 | 0.56 |
| ▸ | DRD2 | P14416 | 2/20 | 0.56 |
| ▸ | DRD3 | P35462 | 2/20 | 0.56 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.56 |
| ▸ | HTR3B | O95264 | 2/20 | 0.56 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.56 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.56 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | HTR6 | P50406 | 1/20 | 0.56 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | HTR7 | P34969 | 6/20 | 0.54 |
| ▸ | HTR2B | P41595 | 2/20 | 0.50 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.46 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6968611 | 0.82 | G6PD (0.59) | NR1H3NR1H2 | |
| SCHEMBL7054984 | 0.76 | HTR7 (0.68) | HTR3ADRD2DRD3HTR3EHTR3B | |
| SCHEMBL7689616 | 0.76 | NR1H3 (0.71) | LMNANR1H3NR1H2 | |
| SCHEMBL6676139 | 0.74 | MEN1 (0.68) | NR1H3NR1H2 | |
| SCHEMBL10075919 | 0.73 | HTR7 (0.71) | HTR3ADRD2DRD3HTR3EHTR3B | |
| SCHEMBL7059249 | 0.73 | HTR3A (0.65) | HTR3ADRD2DRD3HTR3EHTR3B | |
| SCHEMBL12963920 | 0.73 | KMT2A (0.58) | HTR3AHTR3EHTR3BHTR3DHTR3C | |
| SCHEMBL379 | 0.73 | HTR3A (1.00) | HTR3ADRD2DRD3HTR3EHTR3B | |
| SCHEMBL29396943 | 0.73 | HTR3A (1.00) | HTR3ADRD2DRD3HTR3EHTR3B | |
| SCHEMBL6366499 | 0.73 | HTR3A (1.00) | HTR3ADRD2DRD3HTR3EHTR3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6399614-B1 | TREATING NEUROMUSCULAR DYSFUNCTION OF LOWER URINARY TRACT VIA PERIPHERAL OR CENTRAL NERVOUS SYSTEM; SEROTONIN RECEPTOR ANTAGONIST | RECORDATI S.A. CHEMICAL AND PHARMACEUTICAL COMPANY (CH) | 2002-06-04 | — | — | US | disclosed |