Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3A | P46098 | 3/20 | 0.65 |
| ▸ | HTR6 | P50406 | 3/20 | 0.65 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.65 |
| ▸ | HTR3B | O95264 | 2/20 | 0.65 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.65 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.65 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.65 |
| ▸ | DRD2 | P14416 | 1/20 | 0.65 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.65 |
| ▸ | DRD3 | P35462 | 1/20 | 0.65 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.65 |
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | MAPT | P10636 | 1/20 | 0.63 |
| ▸ | HTR7 | P34969 | 7/20 | 0.55 |
| ▸ | HTR1A | P08908 | 6/20 | 0.53 |
| ▸ | HTR2A | P28223 | 1/20 | 0.50 |
| ▸ | HTR5A | P47898 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6963568 | 0.88 | HTR6 (0.65) | HTR3AHTR6HTR3EHTR3BHTR3D | |
| SCHEMBL1298490 | 0.87 | HTR1A (0.59) | HTR3AHTR6HTR3EHTR3BHTR3D | |
| SCHEMBL23708324 | 0.86 | ALDH1A1 (0.57) | HTR3AHTR6HTR3EHTR3BHTR3D | |
| SCHEMBL7054984 | 0.86 | HTR7 (0.68) | HTR3AHTR6HTR3EHTR3BHTR3D | |
| SCHEMBL7055686 | 0.85 | HTR1A (0.50) | HTR3AHTR6HTR3EHTR3BHTR3D | |
| SCHEMBL27930047 | 0.82 | PRKDC (0.50) | DRD2CYP2C19DRD3LMNAMAPT | |
| SCHEMBL6560075 | 0.80 | ADRB1 (0.62) | HTR3AHTR6HTR3EHTR3BHTR3D | |
| SCHEMBL379 | 0.79 | HTR3A (1.00) | HTR3AHTR6HTR3EHTR3BHTR3D | |
| SCHEMBL29396943 | 0.79 | HTR3A (1.00) | HTR3AHTR6HTR3EHTR3BHTR3D | |
| SCHEMBL6366499 | 0.79 | HTR3A (1.00) | HTR3AHTR6HTR3EHTR3BHTR3D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003028728-A1 | 4-(4-SUBSTITUTED PIPERAZINYL-1YL)-BUTYLCARBOXAMIDES AS D3 DOPAMINE SUBTYPE SELECTIVE LIGANDS | Richter Gedeon Vegyészeti Gyár Rt. (HU) | 2003-04-10 | — | — | WO | disclosed |