Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 2/20 | 0.49 |
| ▸ | THRB | P10828 | 2/20 | 0.49 |
| ▸ | SLC6A5 | Q9Y345 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.39 |
| ▸ | TUBB | P07437 | 1/20 | 0.39 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.39 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.39 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.39 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7735407 | 0.83 | TRPV1 (0.43) | SLC6A5HPGD | |
| SCHEMBL7737426 | 0.78 | KMT2A (0.50) | THRATHRBKMT2AMEN1ALDH1A1 | |
| SCHEMBL7725105 | 0.76 | FFAR4 (0.46) | THRATHRBSLC6A5SMN1; SMN2LMNA | |
| SCHEMBL16233225 | 0.73 | SLC6A5 (0.54) | SLC6A5ALDH1A1SMN1; SMN2 | |
| SCHEMBL7737564 | 0.72 | PTPN1 (0.45) | THRATHRBKMT2AKDM4EMEN1 | |
| SCHEMBL7734098 | 0.72 | LTB4R (0.40) | THRATHRBKDM4EHDAC8 | |
| SCHEMBL8431883 | 0.71 | SLC6A5 (0.55) | SLC6A5KMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL9676577 | 0.71 | BPTF (0.48) | THRATHRBSLC6A5KMT2AKDM4E | |
| SCHEMBL29287207 | 0.71 | THRA (0.56) | THRATHRBHPGDSMN1; SMN2PDE4B | |
| SCHEMBL5989205 | 0.71 | HDAC8 (0.52) | KMT2AKDM4EMEN1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6376546-B1 | ANTIALLERGENS | ASAHI KASEI KABUSHIKI KAISHA (JP) | 2002-04-23 | — | — | US | disclosed |
| EP-1024130-A1 | BIPHENYL-5-ALKANOIC ACID DERIVATIVES AND USE THEREOF | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 2000-08-02 | — | — | EP | disclosed |