Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | S1PR4 | O95977 | 3/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.34 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7731117 | 0.82 | FAAH (0.35) | DAGLAPTPN1HDAC3HDAC4HDAC1 | |
| SCHEMBL7723163 | 0.82 | HPGD (0.39) | CYP1A2CYP2C9CYP2C19L3MBTL1KMT2A | |
| SCHEMBL7733852 | 0.77 | LMNA (0.37) | CYP3A4CYP2C19DAGLAHDAC1KMT2A | |
| Trifluoroacetic Acid SCHEMBL7734124 | 0.76 | CYP1A2 (0.42) | IDO1S1PR4S1PR1CYP1A2CYP3A4 | |
| Trifluoroacetic Acid SCHEMBL5411341 | 0.73 | TAAR1 (0.49) | IDO1S1PR4S1PR1CYP1A2CYP3A4 | |
| SCHEMBL7735579 | 0.73 | CYP1A2 (0.44) | IDO1CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL7734127 | 0.69 | CYP3A4 (0.38) | S1PR4S1PR1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL7731071 | 0.68 | BCHE (0.45) | ALOX12PTPN1HDAC3HDAC4HDAC1 | |
| SCHEMBL3225709 | 0.65 | TAAR1 (0.61) | IDO1L3MBTL1ALOX12KMT2AALDH1A1 | |
| SCHEMBL12858901 | 0.64 | IDO1 (0.72) | IDO1CYP1A2CYP3A4CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6436980-B1 | TRANSPORT PROTEIN SUPPRESSORS; MICROBIOCIDES | ESSENTIAL THERAPEUTICS, INC. | 2002-08-20 | — | — | US | disclosed |
| US-6204279-B1 | SECONDARY AMIDE CONTAINING BENZOXAZOLE DERIVATIVES | MICROCIDE PHARMACEUTICALS, INC. | 2001-03-20 | — | — | US | disclosed |