Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | XDH | P47989 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CETP | P11597 | 3/20 | 0.32 |
| ▸ | P2RY14 | Q15391 | 3/20 | 0.32 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | METAP2 | P50579 | 1/20 | 0.31 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.31 |
| ▸ | CASP3 | P42574 | 1/20 | 0.31 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.31 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.31 |
| ▸ | KIF11 | P52732 | 2/20 | 0.30 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7731117 | 0.90 | FAAH (0.35) | XDHDAGLAHDAC1 | |
| SCHEMBL7732045 | 0.89 | CTSL (0.36) | DAGLA | |
| SCHEMBL7734187 | 0.88 | F9 (0.30) | METAP2 | |
| Trifluoroacetic Acid SCHEMBL7733845 | 0.78 | LMNA (0.39) | LMNAKMT2AXDHSMN1; SMN2TP53 | |
| SCHEMBL7734130 | 0.77 | IDO1 (0.39) | KMT2ADAGLAHDAC1CYP3A4CYP2C19 | |
| SCHEMBL7723163 | 0.76 | HPGD (0.39) | KMT2ASMN1; SMN2CYP2C19 | |
| SCHEMBL7732452 | 0.75 | LMNA (0.42) | LMNAKMT2AXDHSMN1; SMN2TP53 | |
| SCHEMBL7736136 | 0.74 | XDH (0.46) | LMNAKMT2AXDHSMN1; SMN2TP53 | |
| SCHEMBL7858147 | 0.74 | XDH (0.46) | LMNAKMT2AXDHSMN1; SMN2TP53 | |
| SCHEMBL7731051 | 0.70 | LMNA (0.39) | LMNAKMT2ATP53CYP3A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6436980-B1 | TRANSPORT PROTEIN SUPPRESSORS; MICROBIOCIDES | ESSENTIAL THERAPEUTICS, INC. | 2002-08-20 | — | — | US | disclosed |
| US-6204279-B1 | SECONDARY AMIDE CONTAINING BENZOXAZOLE DERIVATIVES | MICROCIDE PHARMACEUTICALS, INC. | 2001-03-20 | — | — | US | disclosed |