Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | STAT3 | P40763 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7734840 | 0.89 | PDE4A (0.40) | — | |
| SCHEMBL7737540 | 0.85 | MAPT (0.44) | MAPTKMT2AMEN1SMN1; SMN2STAT3 | |
| SCHEMBL7735654 | 0.82 | NPC1 (0.42) | MAPTKMT2AMEN1NPC1RAB9A | |
| SCHEMBL7737473 | 0.82 | MEN1 (0.39) | MAPTKMT2AMEN1SMN1; SMN2NPC1 | |
| SCHEMBL7733971 | 0.81 | MAPT (0.46) | MAPTKMT2AMEN1SMN1; SMN2NPC1 | |
| SCHEMBL7734786 | 0.81 | PDE4B (0.41) | — | |
| SCHEMBL7724860 | 0.79 | ALDH1A1 (0.47) | MAPTKMT2AMEN1SMN1; SMN2STAT3 | |
| SCHEMBL7734102 | 0.78 | TSHR (0.43) | MAPTKMT2AMEN1SMN1; SMN2STAT3 | |
| SCHEMBL7737446 | 0.77 | PGK1 (0.35) | KMT2AMEN1ALDH1A1 | |
| SCHEMBL7679979 | 0.77 | DHFR (0.34) | MAPTKMT2AMEN1SMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6372770-B1 | TREATING A MAMMAL SUFFERING FROM A DISEASE STATE SELECTED FROM THE GROUP CONSISTING OF ASTHMA, ALLERGIES, INFLAMMATION, DEPRESSION, DEMENTIA, ATOPIC DISEASES, RHINITIS AND DISEASE STATES ASSOCIATED WITH ABNORMALLY HIGH PHYSIOLOGICAL LEVELS OF | EURO-CELTIQUE, S.A. | 2002-04-16 | — | — | US | claimed |