Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 4/20 | 0.40 |
| ▸ | PRSS2 | P07478 | 4/20 | 0.40 |
| ▸ | PRSS3 | P35030 | 4/20 | 0.40 |
| ▸ | TPSAB1 | Q15661 | 4/20 | 0.40 |
| ▸ | SRC | P12931 | 1/20 | 0.36 |
| ▸ | ZAP70 | P43403 | 1/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.35 |
| ▸ | CTSB | P07858 | 1/20 | 0.35 |
| ▸ | CTSS | P25774 | 1/20 | 0.35 |
| ▸ | PLAU | P00749 | 1/20 | 0.35 |
| ▸ | CCR3 | P51677 | 1/20 | 0.34 |
| ▸ | ITGB3 | P05106 | 4/20 | 0.34 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.34 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.34 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MMP7 | P09237 | 1/20 | 0.34 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL7731056 | 0.93 | PRSS1 (0.38) | PRSS1PRSS2PRSS3TPSAB1LTA4H | |
| Trifluoroacetic Acid SCHEMBL7732324 | 0.90 | SLC7A11 (0.37) | PRSS1PRSS2PRSS3TPSAB1SRC | |
| SCHEMBL7732329 | 0.88 | ZAP70 (0.34) | PRSS1PRSS2PRSS3TPSAB1SRC | |
| Trifluoroacetic Acid SCHEMBL7735541 | 0.86 | CCR3 (0.41) | PRSS1PRSS2PRSS3TPSAB1SRC | |
| Trifluoroacetic Acid SCHEMBL7733824 | 0.83 | MMP2 (0.39) | SRCZAP70LTA4HERAP2LNPEP | |
| SCHEMBL7733828 | 0.82 | DAGLA (0.38) | SRCZAP70LTA4HERAP2LNPEP | |
| SCHEMBL7733597 | 0.79 | MAPT (0.51) | CASP1CTSLCTSBCTSSCCR3 | |
| SCHEMBL7730721 | 0.78 | LTA4H (0.40) | SRCZAP70LTA4HERAP2LNPEP | |
| SCHEMBL7735836 | 0.78 | SLC1A3 (0.40) | PRSS1PRSS2PRSS3TPSAB1CASP1 | |
| Trifluoroacetic Acid SCHEMBL7723297 | 0.77 | RAB9A (0.41) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6436980-B1 | TRANSPORT PROTEIN SUPPRESSORS; MICROBIOCIDES | ESSENTIAL THERAPEUTICS, INC. | 2002-08-20 | — | — | US | disclosed |
| US-6204279-B1 | SECONDARY AMIDE CONTAINING BENZOXAZOLE DERIVATIVES | MICROCIDE PHARMACEUTICALS, INC. | 2001-03-20 | — | — | US | disclosed |