Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7737672 | 0.82 | PTGIR (0.44) | SLC6A4SLC6A3 | |
| SCHEMBL7736944 | 0.82 | PTGIR (0.60) | SLC6A4SLC6A3 | |
| SCHEMBL7960362 | 0.79 | SIGMAR1 (0.46) | SIGMAR1SLC6A4SLC6A3 | |
| SCHEMBL7729866 | 0.76 | DRD2 (0.38) | SIGMAR1SLC6A4 | |
| SCHEMBL10357800 | 0.68 | SIGMAR1 (0.81) | SIGMAR1SLC6A4SLC6A3 | |
| SCHEMBL7948766 | 0.68 | SIGMAR1 (0.47) | SIGMAR1 | |
| SCHEMBL7948728 | 0.66 | PTGIR (0.54) | SLC6A4SLC6A3 | |
| SCHEMBL7736556 | 0.64 | HTR7 (0.46) | SLC6A4 | |
| SCHEMBL7960415 | 0.63 | HTR2C (0.51) | SIGMAR1 | |
| Perastine SCHEMBL1506306 | 0.63 | CYP3A4 (0.83) | SIGMAR1SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6407096-B1 | 1,4-BENZOTHIAZINE AND 1,4-BENZOXAZINE DERIVATIVES; HYPOTENSIVE, ANTIISCHEMIC, ANTIALLERGEN, ANTIASTHMATIC AND ANTICOAGULANT AGENTS; CARDIOVASCULAR DISORDERS | TORAY INDUSTRIES, INC. (JP) | 2002-06-18 | — | — | US | disclosed |
| EP-1028113-A1 | FUSED BENZENE HETEROCYCLE DERIVATIVES AND UTILIZATION THEREOF | TORAY INDUSTRIES, INC. (JP) | 2000-08-16 | — | — | EP | disclosed |