Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.30 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7739145 | 0.73 | PTGS1 (0.36) | MEN1KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL7738443 | 0.71 | ELANE (0.33) | MEN1KMT2AKDM4EHSD17B10ALDH1A1 | |
| SCHEMBL29793830 | 0.63 | HMGB1 (0.44) | MEN1KMT2AKDM4EHSD17B10ALDH1A1 | |
| SCHEMBL22160243 | 0.63 | HMGB1 (0.44) | MEN1KMT2AKDM4EHSD17B10ALDH1A1 | |
| SCHEMBL2331029 | 0.62 | SMN1; SMN2 (0.51) | MEN1KMT2AKDM4EHSD17B10ALDH1A1 | |
| SCHEMBL3959577 | 0.62 | SMN1; SMN2 (0.51) | MEN1KMT2AKDM4EHSD17B10ALDH1A1 | |
| Methyl Alcohol SCHEMBL8740643 | 0.61 | SMN1; SMN2 (0.50) | MEN1KMT2AKDM4EHSD17B10ALDH1A1 | |
| SCHEMBL2240589 | 0.60 | GABRA1 (0.43) | MEN1KMT2AKDM4EALDH1A1MAPT | |
| Acetic Acid SCHEMBL27930639 | 0.59 | TDP1 (0.54) | MEN1KMT2AKDM4EHSD17B10ALDH1A1 | |
| Acetic Acid SCHEMBL27930745 | 0.59 | GABRA1 (0.43) | MEN1KMT2AKDM4EHSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6416861-B1 | COMBINATORIAL CHEMISTRY | NORTHWESTERN UNIVERSITY | 2002-07-09 | — | — | US | disclosed |
| WO-2000049022-A2 | ORGANOSILICON COMPOUNDS AND USES THEREOF | NORTHWESTERN UNIVERSITY (US) | 2000-08-24 | — | — | WO | disclosed |