Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | KMO | O15229 | 2/20 | 0.38 |
| ▸ | DRD2 | P14416 | 2/20 | 0.38 |
| ▸ | HTR2A | P28223 | 2/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7736555 | 0.82 | PTGIR (0.47) | PTGIRALDH1A1HTR6DRD2HTR2A | |
| SCHEMBL7737346 | 0.81 | PTGIR (0.49) | PTGIRALDH1A1DRD2HTR2AMCHR1 | |
| SCHEMBL7739689 | 0.81 | ALOX12 (0.40) | ALDH1A1HTR6HPGDKMODRD2 | |
| SCHEMBL7730040 | 0.79 | ALOX12 (0.53) | ALDH1A1KDM4EHPGDL3MBTL1MEN1 | |
| SCHEMBL7736507 | 0.77 | PTGIR (0.63) | PTGIRALDH1A1PTGDR2KDM4EHPGD | |
| SCHEMBL7729988 | 0.77 | HTR6 (0.41) | ALDH1A1HTR6KMODRD2HTR2A | |
| SCHEMBL3584551 | 0.76 | HTR6 (0.41) | ALDH1A1HTR6KMODRD2HTR2A | |
| SCHEMBL7737250 | 0.72 | PTGIR (0.46) | PTGIRPTGDR2ALOX12 | |
| SCHEMBL7522216 | 0.71 | PARP1 (0.50) | ALDH1A1PTGDR2KDM4EHPGDTDP1 | |
| SCHEMBL7736480 | 0.71 | ALDH1A1 (0.41) | ALDH1A1POLBMEN1KMT2ACHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6407096-B1 | 1,4-BENZOTHIAZINE AND 1,4-BENZOXAZINE DERIVATIVES; HYPOTENSIVE, ANTIISCHEMIC, ANTIALLERGEN, ANTIASTHMATIC AND ANTICOAGULANT AGENTS; CARDIOVASCULAR DISORDERS | TORAY INDUSTRIES, INC. (JP) | 2002-06-18 | — | — | US | disclosed |
| EP-1028113-A1 | FUSED BENZENE HETEROCYCLE DERIVATIVES AND UTILIZATION THEREOF | TORAY INDUSTRIES, INC. (JP) | 2000-08-16 | — | — | EP | disclosed |