Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 3/20 | 0.37 |
| ▸ | HTR1D | P28221 | 3/20 | 0.37 |
| ▸ | HTR1B | P28222 | 3/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CBX7 | O95931 | 1/20 | 0.36 |
| ▸ | CDYL2 | Q8N8U2 | 1/20 | 0.36 |
| ▸ | CDYL | Q9Y232 | 1/20 | 0.36 |
| ▸ | CDY1; CDY1B | Q9Y6F8 | 1/20 | 0.36 |
| ▸ | NMT1 | P30419 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7739735 | 0.91 | HTR1A (0.39) | ALDH1A1HTR1AHTR1DHTR1BSLC6A4 | |
| SCHEMBL7736480 | 0.82 | ALDH1A1 (0.41) | ALDH1A1TSHRHSD17B10MAPTHTR1A | |
| SCHEMBL7737346 | 0.79 | PTGIR (0.49) | ALDH1A1TSHRHSD17B10POLBMEN1 | |
| SCHEMBL27688254 | 0.71 | KMT2A (0.44) | ALDH1A1TSHRHTR1AHTR1DHTR1B | |
| SCHEMBL4969042 | 0.69 | HSD17B10 (0.46) | ALDH1A1TSHRHSD17B10MAPTPOLB | |
| SCHEMBL27707632 | 0.67 | KMT2A (0.44) | ALDH1A1TSHRPOLBCBX7CDYL2 | |
| SCHEMBL7737376 | 0.66 | TBXA2R (0.48) | ALDH1A1POLBTBXA2RPTGIR | |
| SCHEMBL7737236 | 0.65 | TBXA2R (0.48) | ALDH1A1POLBTBXA2RPTGIR | |
| SCHEMBL7739672 | 0.64 | KDM4E (0.38) | ALDH1A1MAPTPOLBMEN1KMT2A | |
| SCHEMBL7737187 | 0.64 | HTR6 (0.41) | ALDH1A1MAPTHTR1AKCNH2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6407096-B1 | 1,4-BENZOTHIAZINE AND 1,4-BENZOXAZINE DERIVATIVES; HYPOTENSIVE, ANTIISCHEMIC, ANTIALLERGEN, ANTIASTHMATIC AND ANTICOAGULANT AGENTS; CARDIOVASCULAR DISORDERS | TORAY INDUSTRIES, INC. (JP) | 2002-06-18 | — | — | US | disclosed |
| EP-1028113-A1 | FUSED BENZENE HETEROCYCLE DERIVATIVES AND UTILIZATION THEREOF | TORAY INDUSTRIES, INC. (JP) | 2000-08-16 | — | — | EP | disclosed |