Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.38 |
| ▸ | KMO | O15229 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.37 |
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
| ▸ | EDNRB | P24530 | 1/20 | 0.36 |
| ▸ | EDNRA | P25101 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CBX7 | O95931 | 1/20 | 0.34 |
| ▸ | CDYL2 | Q8N8U2 | 1/20 | 0.34 |
| ▸ | CDYL | Q9Y232 | 1/20 | 0.34 |
| ▸ | CDY1; CDY1B | Q9Y6F8 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7737834 | 0.81 | PTGIR (0.43) | ALOX12KMT2APOLBHSD17B10DRD2 | |
| SCHEMBL7729988 | 0.74 | HTR6 (0.41) | KMT2ADRD2HTR2AMCHR1KMO | |
| SCHEMBL3584551 | 0.73 | HTR6 (0.41) | KMT2ADRD2HTR2AMCHR1KMO | |
| SCHEMBL4973366 | 0.70 | KMO (0.49) | ALOX12KMT2APOLBHSD17B10KMO | |
| SCHEMBL11287448 | 0.68 | KMT2A (0.46) | KMT2AHTR2ATSHR | |
| SCHEMBL4969042 | 0.67 | HSD17B10 (0.46) | ALOX12KMT2APOLBHSD17B10ALDH1A1 | |
| SCHEMBL7358743 | 0.67 | ALDH1A1 (0.61) | KMT2APOLBALDH1A1MEN1CBX7 | |
| SCHEMBL4971237 | 0.67 | TSHR (0.50) | ALOX12KMT2APOLBKMOALDH1A1 | |
| SCHEMBL7730166 | 0.67 | CHRM1 (0.38) | ALOX12KMT2APOLBHSD17B10DRD2 | |
| SCHEMBL7736578 | 0.67 | DRD2 (0.41) | KMT2APOLBHSD17B10DRD2HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6407096-B1 | 1,4-BENZOTHIAZINE AND 1,4-BENZOXAZINE DERIVATIVES; HYPOTENSIVE, ANTIISCHEMIC, ANTIALLERGEN, ANTIASTHMATIC AND ANTICOAGULANT AGENTS; CARDIOVASCULAR DISORDERS | TORAY INDUSTRIES, INC. (JP) | 2002-06-18 | — | — | US | disclosed |