SCHEMBL7738668

SCHEMBL7738668

CN1C(=O)CCN1c1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.42
KMT2A Q03164 3/20 0.42
NPC1 O15118 2/20 0.42
RAB9A P51151 2/20 0.42
GSK3A P49840 2/20 0.41
GSK3B P49841 2/20 0.41
ALOX5 P09917 2/20 0.40
PTGS1 P23219 2/20 0.40
G6PD P11413 1/20 0.40
ALOX15 P16050 1/20 0.40
ALOX12 P18054 1/20 0.40
PTGS2 P35354 1/20 0.40
DDB1 Q16531 1/20 0.39
CRBN Q96SW2 1/20 0.39
MGLL Q99685 1/20 0.39
ALDH1A1 P00352 3/20 0.38
KDM4E B2RXH2 1/20 0.38
CYP1A2 P05177 1/20 0.38
CHRM2 P08172 1/20 0.38
CYP3A4 P08684 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22781366 0.81 ALOX5 (0.43) MEN1KMT2AGSK3AGSK3BALOX5
SCHEMBL5418407 0.78 MEN1 (0.43) MEN1KMT2ANPC1RAB9AGSK3A
SCHEMBL8194180 0.76 MEN1 (0.42) MEN1KMT2ANPC1RAB9AGSK3A
SCHEMBL27518814 0.76 KMT2A (0.42) MEN1KMT2ANPC1RAB9AGSK3A
SCHEMBL5674146 0.74 ALDH1A1 (0.45) MEN1KMT2ANPC1RAB9AALOX5
SCHEMBL11439756 0.74 ALDH1A1 (0.44) MEN1KMT2ANPC1RAB9AALDH1A1
SCHEMBL9465620 0.73 PRKCA (0.40) MEN1KMT2ANPC1RAB9AGSK3B
SCHEMBL28479963 0.72 KMT2A (0.38) MEN1KMT2ANPC1RAB9AGSK3A
SCHEMBL10418452 0.72 KMT2A (0.38) MEN1KMT2ANPC1RAB9AGSK3A
SCHEMBL9453365 0.72 MEN1 (0.38) MEN1KMT2ANPC1RAB9AGSK3A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8212050-B2 Amidine compounds and herbicides NIPPON SODA CO., LTD. (JP) 2012-07-03 US disclosed
US-20110301355-A1 Amidine compounds and herbicides NIPPON SODA CO., LTD. (JP) 2011-12-08 US disclosed
US-7186500-B2 Silver halide photographic lightsensitive material FUJI PHOTO FILM CO., LTD. (JP) 2007-03-06 US disclosed
US-7186500-B2 Silver halide photographic lightsensitive material FUJI PHOTO FILM CO., LTD. (JP) 2007-03-06 US disclosed
US-6410216-B1 SILVER HALIDE FILM; NONDIFFUSING BALLASTED SULPHONHYDRAZIDE COLOR DEVELOPING AGENT AND 3-PYRIDINOL PHOTOGRAPHIC COLOR COUPLER IN DROPLETS OF HIGH BOILING SOLVENT; MAGENTA AZO DYE EASTMAN KODAK COMPANY 2002-06-25 US disclosed
US-5994040-A USING A HYDROXYANILINE COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1999-11-30 US disclosed
US-5196566-A Tris(alkoxy)benzyl esters for use in linking protected amino acid or peptides to a support REGENTS OF THE UNIVERSITY OF MINNESOTA (US) 1993-03-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110301355-A1 Amidine compounds and herbicides DDT, GATD3, PAM MEN1 1805/4885KMT2A 1227/4885NPC1 4594/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.