SCHEMBL9453365

SCHEMBL9453365

O=C1CCN(c2ccccc2)N1CO

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
NPC1 O15118 1/20 0.38
RAB9A P51151 1/20 0.38
HSD17B10 Q99714 1/20 0.37
ALOX5 P09917 1/20 0.37
G6PD P11413 1/20 0.37
ALOX15 P16050 1/20 0.37
ALOX12 P18054 1/20 0.37
PTGS1 P23219 1/20 0.37
PTGS2 P35354 1/20 0.37
APOBEC3A P31941 1/20 0.37
RECQL P46063 1/20 0.37
APOBEC3G Q9HC16 1/20 0.37
GSK3A P49840 1/20 0.37
GSK3B P49841 1/20 0.37
CTSG P08311 2/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
DDB1 Q16531 1/20 0.36
CRBN Q96SW2 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10417511 0.83 HTT (0.41) MEN1KMT2ARAB9AALOX5ALOX12
SCHEMBL9465620 0.79 PRKCA (0.40) MEN1KMT2ANPC1RAB9AALOX5
SCHEMBL10911511 0.76 HTR1A (0.43) MEN1KMT2ANPC1RAB9AHSD17B10
SCHEMBL8831808 0.76 KCNH2 (0.36) MEN1KMT2ANPC1RAB9AALOX5
SCHEMBL27518814 0.76 KMT2A (0.42) MEN1KMT2ANPC1RAB9AHSD17B10
SCHEMBL7099330 0.75 RAB9A (0.38) NPC1RAB9AAPOBEC3ARECQLAPOBEC3G
SCHEMBL13777921 0.75 KMT2A (0.47) MEN1KMT2ANPC1RAB9AGSK3A
SCHEMBL10407212 0.74 ALDH1A1 (0.43) MEN1KMT2AL3MBTL1ALDH1A1CYP2C9
SCHEMBL5418407 0.73 MEN1 (0.43) MEN1KMT2ANPC1RAB9AALOX5
SCHEMBL7738668 0.72 MEN1 (0.42) MEN1KMT2ANPC1RAB9AALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0564902-A1 Package for photographic chemicals ILFORD Limited (GB) 1993-10-13 EP disclosed
US-5230981-A Polymer image formed where oxidation product of reducing agent has not formed FUJI PHOTO FILM CO., LTD. (JP) 1993-07-27 US disclosed
US-5166040-A Light sensitive silver halide emulsions for images FUJI PHOTO FILM CO., LTD. (JP) 1992-11-24 US disclosed
US-5004667-A Can be endowed with stickiness with change in pH value CANON KABUSHIKI KAISHA (JP) 1991-04-02 US disclosed
EP-0321161-A2 Photosensitive material, and image formation process and image formation apparatus using same CANON KABUSHIKI KAISHA (JP) 1989-06-21 EP disclosed
EP-0202490-A1 Method for forming a polymer image and image recording material therefor FUJI PHOTO FILM CO., LTD. (JP) 1986-11-26 EP disclosed